From plants to pathogens, fruit flies to fungi and hamsters to humans, Naked Genetics takes a look at the science of genes. With in-depth interviews and the latest discoveries from the world of genetics, tune in for a look inside your genes...//www.silkstaq.com/podcasts/naked-genetics en 30 金宝搏app最新下载 //www.silkstaq.com/podcasts/naked-genetics Wed, 14 Apr 2021 11:48:35 +0100 Wed, 14 Apr 2021 11:46:10 +0100 Naked Scientists Pod Publisher //www.silkstaq.com/podcasts/naked-genetics //www.silkstaq.com/sites/default/files/media/media/images/NS_Genetics_1400.png Naked Genetics: Taking a look inside your genes 情景 菲尔·桑塞姆 From plants to pathogens, fruit flies to fungi and hamsters to humans, Naked Genetics takes a look at the science of genes. With in-depth interviews and the latest discoveries from the world of genetics, tune in for a look inside your genes... 188bet体育投注官网 chris@thenakedscientists.com no dna, genetics,genes,molecular biology, gene editing, genomics, heredity, RNA COVID In Your Genes: The Risk Factors 97//www.silkstaq.com/podcasts/naked-scientists-podcast/covid-your-genes-risk-factors Wed, 14 Apr 2021 11:46:10 +0100 Do our genes control how we respond to COVID? The answer is in - and it's yes... Do our genes control how we respond to COVID? The question has been nagging at the world since the pandemic began. Now we have the answer - and it's yes. In this programme, geneticist Nathan Pearson uncovers the specific bits of DNA that make you more likely to catch coronavirus, as well as the bits that might make you sicker.... Like this podcast? Please help us by supporting the Naked Scientists Do our genes control how we respond to COVID? The question has been nagging at the world since the pandemic began. Now we have the answer - and it's yes. In this programme, geneticist Nathan Pearson uncovers the specific bits of DNA that make you more likely to catch coronavirus, as well as the bits that might make you sicker.... Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:29:46 host genetics,covid genes,covid risk factors,coronavirus risk factors,covid-19 host genetics initiative,nathan pearson //www.silkstaq.com/sites/default/files/media/podcasts/episodes/guid/JiAJRC5AEpPX The Genes Who Came in for the Cold 96//www.silkstaq.com/podcasts/naked-genetics/genes-who-came-cold Wed, 17 Mar 2021 20:12:10 +0000 In this month's programme, meet the genes that help us tolerate - and even enjoy - being extremely chilly... How do we cope at the extremes of low temperature? Across the world, groups of people have historically made their home in icy and inhospitable landscapes... and even today, groups of thrill seekers push their bodies to the limits by going swimming in water close to freezing. In this month's programme, genes that help us handle - and even enjoy - being very cold. We've got two stories from the ancient ice, including the oldest ever DNA; plus, two modern genes found to be helping us out in interesting ways, whenever things get particularly chilly... Like this podcast? Please help us by supporting the Naked Scientists How do we cope at the extremes of low temperature? Across the world, groups of people have historically made their home in icy and inhospitable landscapes... and even today, groups of thrill seekers push their bodies to the limits by going swimming in water close to freezing. In this month's programme, genes that help us handle - and even enjoy - being very cold. We've got two stories from the ancient ice, including the oldest ever DNA; plus, two modern genes found to be helping us out in interesting ways, whenever things get particularly chilly... Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:29:37 trpm8,cold water swimmer,cold water swimming,Anna Ploszajski,ice bath,ancient DNA,mammoth dna,oldest dog,first dog americas,love dalen,oldest dna //www.silkstaq.com/sites/default/files/media/podcasts/episodes/guid/wVToRe7oBhqM How To Tell Coronavirus Variants Apart 95//www.silkstaq.com/podcasts/naked-genetics/how-tell-coronavirus-variants-apart Wed, 24 Feb 2021 12:32:04 +0000 Meet the most critical coronavirus variants. Plus: catching a serial killer; and fish gaining limbs... We're looking at the most critical variants of the coronavirus, and finding out how to tell whether they're flummoxing COVID vaccines. Plus: the cost of catching a serial killer; DNA with four strands instead of two; and a mutant fish whose fins have started turning into limbs! Like this podcast? Please help us by supporting the Naked Scientists We're looking at the most critical variants of the coronavirus, and finding out how to tell whether they're flummoxing COVID vaccines. Plus: the cost of catching a serial killer; DNA with four strands instead of two; and a mutant fish whose fins have started turning into limbs! Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:28:32 covid,coronavirus variants,covid variants,pfizer vaccine,pei-yong shi,uk variant,south african variant,g-quadruplex,g-quadruplexes,golden state killer //www.silkstaq.com/sites/default/files/media/podcasts/episodes/guid/XN9lH3WcTppL Identical Twins: Not Identical? 94//www.silkstaq.com/podcasts/naked-genetics/identical-twins-not-identical Fri, 15 Jan 2021 05:49:00 +0000 This month: mutations in early development, selfish genes in sperm, and COVID vaccine booster shots... Meet the small DNA differences that make their mark by existing in the magical period of early development. We'll hear how mutations in the very first stages of human embryos have bizarre consequences for identical twins; and how even earlier in the process, sperm use selfish genes to get ahead of the competition. Plus, an immunologist untangles mRNA COVID vaccines, from efficacy numbers to delayed booster shots... Like this podcast? Please help us by supporting the Naked Scientists Meet the small DNA differences that make their mark by existing in the magical period of early development. We'll hear how mutations in the very first stages of human embryos have bizarre consequences for identical twins; and how even earlier in the process, sperm use selfish genes to get ahead of the competition. Plus, an immunologist untangles mRNA COVID vaccines, from efficacy numbers to delayed booster shots... Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:28:45 identical twins,monozygotic twins,germline mutations,twin studies,sperm competition,moth lab,covid vaccine,coronavirus vaccine,pfizer vaccine,delayed booster //www.silkstaq.com/sites/default/files/media/podcasts/episodes/guid/KOIASGXPaqy8 RNA vaccines, privacy, and penguins 93//www.silkstaq.com/podcasts/naked-genetics/rna-vaccines-privacy-and-penguins Thu, 17 Dec 2020 05:56:37 +0000 Addressing your questions about the coronavirus vaccine. Plus: quick-change genes, privacy, and penguins... The first group of people in the world have received a 'genetic' vaccine against the coronavirus. What is it, and how does it work? Naked Scientist Chris Smith breaks it down and addresses your concerns. Plus, why some genes have to change rapidly just to stay the same; a new way to keep functional genetic information private; and three new species of penguin arrive on the scene... Like this podcast? Please help us by supporting the Naked Scientists The first group of people in the world have received a 'genetic' vaccine against the coronavirus. What is it, and how does it work? Naked Scientist Chris Smith breaks it down and addresses your concerns. Plus, why some genes have to change rapidly just to stay the same; a new way to keep functional genetic information private; and three new species of penguin arrive on the scene... Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:24:03 covid,coronavirus vaccine,pfizer vaccine,vaccine risky,vaccine unsafe,vaccine dangerous,chris smith,gentoo penguins //www.silkstaq.com/sites/default/files/media/podcasts/episodes/guid/tz2E2rVrEHUQ Mink, Ivory, & a Disease Discovered Backwards 92//www.silkstaq.com/podcasts/naked-genetics/mink-ivory-disease-discovered-backwards Fri, 13 Nov 2020 05:53:57 +0000 Coronavirus in mink, a test to track poached ivory, the genome of a cat, and a new genetic disease... It's a regular Noah's Ark: from the coronavirus strains that have been spreading through minks, to a new DNA test that can track poached elephant ivory, to the genetics of a very useful - and very inbred - cat. Plus: scientists have discovered a brand new genetic disease, via an unlikely approach and an even unlikelier coincidence... Like this podcast? Please help us by supporting the Naked Scientists It's a regular Noah's Ark: from the coronavirus strains that have been spreading through minks, to a new DNA test that can track poached elephant ivory, to the genetics of a very useful - and very inbred - cat. Plus: scientists have discovered a brand new genetic disease, via an unlikely approach and an even unlikelier coincidence... Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:27:11 covid,coronavirus mink,mink farms,elephant ivory,poached ivory,DNA test,cinnamon the cat,cat genome,vexas //www.silkstaq.com/sites/default/files/media/podcasts/episodes/guid/qzpCozZsyGQs Slave Trade, Neanderthals, & COVID 91//www.silkstaq.com/podcasts/naked-genetics/slave-trade-neanderthals-covid Fri, 16 Oct 2020 06:31:12 +0100 A severe COVID risk factor in our genes; tracking the translatlantic slave trade; and a genetics video game... 本周:严重的危险因素COVID comes from Neanderthals; using genes to track the millions transported as slaves across the Atlantic; a doctor runs through the list of what coronavirus mutations are worth watching out for; and learning population genetics from a video game... Like this podcast? Please help us by supporting the Naked Scientists 本周:严重的危险因素COVID comes from Neanderthals; using genes to track the millions transported as slaves across the Atlantic; a doctor runs through the list of what coronavirus mutations are worth watching out for; and learning population genetics from a video game... Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:28:22 slave trade,slavery,covid mutations,covid,coronavirus mutations,covid neanderthals,niche,genetics video game //www.silkstaq.com/sites/default/files/media/podcasts/episodes/guid/sCj9YCFJ7cyF How To Survive Poison 90//www.silkstaq.com/podcasts/naked-genetics/how-survive-poison Mon, 14 Sep 2020 05:28:55 +0100 Bugs do it. And vertebrates - and even humans. How do you eat poison and get away with it? This week, a message from Naked Scientists listener Loretta. "I'm curious if your show might cover some of the most interesting case studies of organisms developing tolerance to severe toxins, what genetic insight this gives us about adaptation and natural selection more broadly, and what some of the tradeoffs might be when evolving to have such tolerances." We're answering her question: how do animals - and even humans - eat poison, and get away with it? Like this podcast? Please help us by supporting the Naked Scientists This week, a message from Naked Scientists listener Loretta. "I'm curious if your show might cover some of the most interesting case studies of organisms developing tolerance to severe toxins, what genetic insight this gives us about adaptation and natural selection more broadly, and what some of the tradeoffs might be when evolving to have such tolerances." We're answering her question: how do animals - and even humans - eat poison, and get away with it? Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:29:54 toxins,sequestering toxins,sequester toxins,eat toxin,eat poison,mithridates,t cell immunity,monarch butterflies,cardiac glycosides //www.silkstaq.com/sites/default/files/media/podcasts/episodes/guid/vWidXtXIFWQG The Inner Lives of Birds 89//www.silkstaq.com/podcasts/naked-genetics/inner-lives-birds Wed, 19 Aug 2020 03:53:03 +0100 Birds can do amazing things. Let's take a look under the wing... 微博推特!我们说的鸟类,和incredible things they can do. Today we're spotlighting five of the coolest recent stories in bird genetics: hummingbirds powering their lightning-fast flight; a gene that controls migration; why males have different colours to females; how light pollution makes sparrows sicker; and the bird trapped for thousands of years under the Siberian ice... Like this podcast? Please help us by supporting the Naked Scientists 微博推特!我们说的鸟类,和incredible things they can do. Today we're spotlighting five of the coolest recent stories in bird genetics: hummingbirds powering their lightning-fast flight; a gene that controls migration; why males have different colours to females; how light pollution makes sparrows sicker; and the bird trapped for thousands of years under the Siberian ice... Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:28:40 bird genetics,bird dna,hummingbirds,hummingbird metabolism,ice bird,sexual dichromatism,west nile virus,bird migration //www.silkstaq.com/sites/default/files/media/podcasts/episodes/guid/BPaMjwby703t Female Mosaicism: The Stronger Sex? 88//www.silkstaq.com/podcasts/naked-genetics/female-mosaicism-stronger-sex Wed, 15 Jul 2020 03:22:00 +0100 Meet the phenomenon that seems to help females live longer, see colour better, and even survive COVID-19... The same thing that makes the patchwork colours on a tortoiseshell cat, also - according to some - is why human females live longer, see colour better, and even more often survive the coronavirus. It's all thanks to having two X chromosomes. Females compensate by switching one of them off, and the result is two distinct groups of cells in the body, each preferring one of the two X's. Welcome to the weird world of female mosaicism... Like this podcast? Please help us by supporting the Naked Scientists The same thing that makes the patchwork colours on a tortoiseshell cat, also - according to some - is why human females live longer, see colour better, and even more often survive the coronavirus. It's all thanks to having two X chromosomes. Females compensate by switching one of them off, and the result is two distinct groups of cells in the body, each preferring one of the two X's. Welcome to the weird world of female mosaicism... Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:27:00 female mosaicism,females are mosaics,mary lyon,sharon moalem,barbara migeon,better half,x inactivation,silenced x //www.silkstaq.com/sites/default/files/media/podcasts/episodes/guid/nr8y89SYFfol Fermented foods: the real deal? 87//www.silkstaq.com/podcasts/naked-genetics/fermented-foods-real-deal Mon, 15 Jun 2020 02:56:52 +0100 We take a look at the trendy world of fermented foods. Are they actually good for you? And if so, why? We take a look at the trendy world of fermented foods. Are they actually good for you? And if so, why? Plus, the latest genetics news: from bacteria that live inside cancer cells, to gene sequencing the dead sea scrolls... Like this podcast? Please help us by supporting the Naked Scientists We take a look at the trendy world of fermented foods. Are they actually good for you? And if so, why? Plus, the latest genetics news: from bacteria that live inside cancer cells, to gene sequencing the dead sea scrolls... Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:29:55 fermented milk,paul cotter,john leech,dead sea scrolls,cancer bacteria,pcr mismatches,ravid straussman,kefir,gut microbiome //www.silkstaq.com/sites/default/files/media/podcasts/episodes/guid/exCw9iQQHYeE ACE2: The Coronavirus Gateway 86//www.silkstaq.com/podcasts/naked-genetics/ace2-coronavirus-gateway Thu, 14 May 2020 02:55:23 +0100 Meet ACE2, the protein in the pandemic spotlight - protector, turned betrayer... Are you one of the many people who take ACE inhibitors or ARBs to treat high blood pressure? Or to help with heart issues or diabetes? In the UK, this is about one in seven people, making these are some of the most common prescription drugs out there; and recently there have been worries that they might make a coronavirus infection worse. The link between the drugs and the virus is a molecule inside everyone's bodies called ACE2. On today's show, meet ACE2, the protein in the spotlight: the bastion of our defenses, that's become the very breach in our walls. Protector, turned betrayer... Like this podcast? Please help us by supporting the Naked Scientists Are you one of the many people who take ACE inhibitors or ARBs to treat high blood pressure? Or to help with heart issues or diabetes? In the UK, this is about one in seven people, making these are some of the most common prescription drugs out there; and recently there have been worries that they might make a coronavirus infection worse. The link between the drugs and the virus is a molecule inside everyone's bodies called ACE2. On today's show, meet ACE2, the protein in the spotlight: the bastion of our defenses, that's become the very breach in our walls. Protector, turned betrayer... Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:34:01 ACE2,ace,angiotensin converting enzyme,coronavirus receptor,covid-19,covid receptor,coronavirus gateway,spike protein,ACE2 genetics,host genetics,covid //www.silkstaq.com/sites/default/files/media/podcasts/episodes/guid/xIKtYCCTI5Ve The Coronavirus Mutation Situation 85//www.silkstaq.com/podcasts/naked-genetics/coronavirus-mutation-situation Wed, 15 Apr 2020 11:46:53 +0100 Underneath this global pandemic is a tiny string of genetic code, whose sequence reveals its nature... In this episode we're taking apart the tiny creature behind this global pandemic. From how looking at the genes of the coronavirus can help figure out the animal it comes from; to the exact ways it's spreading around the world; and even how a hidden mutation is threatening to lead vaccine-makers on a wild goose chase. Plus, Gins & Genes goes virtual; stay tuned to hear what's inside our guest's downstairs toilet... Like this podcast? Please help us by supporting the Naked Scientists In this episode we're taking apart the tiny creature behind this global pandemic. From how looking at the genes of the coronavirus can help figure out the animal it comes from; to the exact ways it's spreading around the world; and even how a hidden mutation is threatening to lead vaccine-makers on a wild goose chase. Plus, Gins & Genes goes virtual; stay tuned to hear what's inside our guest's downstairs toilet... Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:25:03 coronavirus genetics,coronavirus genome,coronavirus genes,neil ward,david matthews,spike protein,arinjay banerjee,moth lab //www.silkstaq.com/sites/default/files/media/podcasts/episodes/guid/QofafdBNf2iu Gene Genealogy & The Lost Family 84//www.silkstaq.com/podcasts/naked-genetics/gene-genealogy-lost-family Sat, 14 Mar 2020 02:05:29 +0000 Direct to consumer DNA tests are excellent at uncovering family history - and family secrets... One of the biggest tech booms of the past half decade has been direct to consumer DNA tests. The results come in the post, and with them come both answers and new questions: questions that tens of thousands of people now have to figure out how to ask. In this episode, a new book from journalist Libby Copeland about a sociological phenomenon and its effects, both grand and intimate... Like this podcast? Please help us by supporting the Naked Scientists One of the biggest tech booms of the past half decade has been direct to consumer DNA tests. The results come in the post, and with them come both answers and new questions: questions that tens of thousands of people now have to figure out how to ask. In this episode, a new book from journalist Libby Copeland about a sociological phenomenon and its effects, both grand and intimate... Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:24:08 the lost family,libby copeland,DNA tests,dna testing,genetic genealogy,23andme,family secrets,family tree,Naked Genetics //www.silkstaq.com/sites/default/files/media/podcasts/episodes/guid/3KSloQ0IaVjo FOXG1综合症:战斗的几率 83//www.silkstaq.com/podcasts/naked-genetics/foxg1-syndrome-fighting-odds Thu, 20 Feb 2020 07:32:53 +0000 FOXG1 Syndrome is one of the rarest genetic disorders out there. Now, meet the people fighting it... Listener Vivek got in touch with a question about a rare genetic disease his son has, called FOXG1 Syndrone. In fact, it's so rare - and so newly-discovered - that only about six hundred people in the world have been diagnosed. Kids with FOXG1 have severe developmental delays; in Vivek's words, "everything that can go wrong - it's gone wrong with him." But the parents of FOXG1 children have been unusually tenacious when it comes to shaping the course of science. In this programme we meet those people blurring the line - metaphorically speaking - between the brain and the heart. Like this podcast? Please help us by supporting the Naked Scientists Listener Vivek got in touch with a question about a rare genetic disease his son has, called FOXG1 Syndrone. In fact, it's so rare - and so newly-discovered - that only about six hundred people in the world have been diagnosed. Kids with FOXG1 have severe developmental delays; in Vivek's words, "everything that can go wrong - it's gone wrong with him." But the parents of FOXG1 children have been unusually tenacious when it comes to shaping the course of science. In this programme we meet those people blurring the line - metaphorically speaking - between the brain and the heart. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:25:08 vivek singha,kush singha,foxg1 syndrome,genetic disease,genetic disorder,genetic condition,foxg1 foundation,nicole johnson,tim rittman,hannah bruce,jae lee //www.silkstaq.com/sites/default/files/media/podcasts/episodes/guid/yksMV3YkOr4x The Fly Infest-agation 82//www.silkstaq.com/podcasts/naked-genetics/fly-infest-agation Tue, 14 Jan 2020 08:42:28 +0000 We got a Christmas present: a small tube of dead flies. Can DNA crack the case? We got a Christmas present from listener Anna: a small plastic tube full of dead flies. They've recently been infesting the hospital where she works. She wants us to figure out what they are, and what caused the infestation. Can DNA crack the case? Plus, the return of Gins & Genes... Like this podcast? Please help us by supporting the Naked Scientists We got a Christmas present from listener Anna: a small plastic tube full of dead flies. They've recently been infesting the hospital where she works. She wants us to figure out what they are, and what caused the infestation. Can DNA crack the case? Plus, the return of Gins & Genes... Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:28:08 序列一只苍蝇,测序一只苍蝇,飞侵扰,广告denbrookes,gene sequencing,fly DNA,fly bacteria,gins and genes,gins & genes,will it sequence //www.silkstaq.com/sites/default/files/media/podcasts/episodes/guid/6Blk03iJjry1 African genetics and ethics 81//www.silkstaq.com/podcasts/naked-genetics/african-genetics-and-ethics Sat, 14 Dec 2019 10:04:37 +0000 The story of the largest ever study of African people's genetics - and the ethical issue that came after... There are very few African studies in genetics. And on the whole, there is a big European bias in the field. In Europe there are resources of hundreds of thousands of individuals' data, like the UK Biobank, and so that's where most research take place. But there's a potential problem: the subtle differences in DNA may start to make a difference the more genetics is used to diagnose and treat diseases. All this is why a number of institutions have collaborated to survey thousands of people's genomes in rural Uganda. In this episode we cover the results of Africa's biggest ever genetics study;... Like this podcast? Please help us by supporting the Naked Scientists There are very few African studies in genetics. And on the whole, there is a big European bias in the field. In Europe there are resources of hundreds of thousands of individuals' data, like the UK Biobank, and so that's where most research take place. But there's a potential problem: the subtle differences in DNA may start to make a difference the more genetics is used to diagnose and treat diseases. All this is why a number of institutions have collaborated to survey thousands of people's genomes in rural Uganda. In this episode we cover the results of Africa's biggest ever genetics study;... Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:28:56 deepti gurdasani,Sanger Institute,african genetics,sanger whistleblower,ugandan genome resource,human genetics //www.silkstaq.com/sites/default/files/media/podcasts/episodes/guid/vdPRz0DsvcFX What's in the water? 80//www.silkstaq.com/podcasts/naked-genetics/whats-water Thu, 14 Nov 2019 05:35:06 +0000 We're diving into the stuff that makes up two thirds of the Earth's surface... This month we're diving into the stuff that makes up two thirds of the Earth's surface. Can you use genetics to figure out what's in the water? We put the science to the test by making a geneticist guess our mystery fish. Plus, a story about whales and dolphins: what do you lose when you leave the land? Jump in, the water's fine. Like this podcast? Please help us by supporting the Naked Scientists This month we're diving into the stuff that makes up two thirds of the Earth's surface. Can you use genetics to figure out what's in the water? We put the science to the test by making a geneticist guess our mystery fish. Plus, a story about whales and dolphins: what do you lose when you leave the land? Jump in, the water's fine. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:26:05 environmental dna,marine audit,whale dna,whale genetics,sequencing a fishtank,sequencing a fish tank,sequencing a piranha,sequencing piranha water //www.silkstaq.com/sites/default/files/media/podcasts/episodes/guid/emN11OtPRnAP Quadrillions: Sequencing the UK Biobank 79//www.silkstaq.com/podcasts/naked-genetics/quadrillions-sequencing-uk-biobank Mon, 14 Oct 2019 06:26:48 +0100 This month on the show, the biggest whole-genome project ever. We're talking in the quadrillions... Half a million genomes. That's how many the UK Biobank has, stored as blood samples in freezers up in Manchester. And in September 2019 they announced a project to sequence every single one of them. It's the obvious next step for the UK Biobank, the research study that began in 2006 and now consists of an enormous biological database: the personal and medical information of its 500,000 volunteers. That data is available to any researcher who applies to use it. But how is this, the biggest whole-genome sequencing project ever, going to work? Who's coughing up the hundreds of millions of pounds... Like this podcast? Please help us by supporting the Naked Scientists Half a million genomes. That's how many the UK Biobank has, stored as blood samples in freezers up in Manchester. And in September 2019 they announced a project to sequence every single one of them. It's the obvious next step for the UK Biobank, the research study that began in 2006 and now consists of an enormous biological database: the personal and medical information of its 500,000 volunteers. That data is available to any researcher who applies to use it. But how is this, the biggest whole-genome sequencing project ever, going to work? Who's coughing up the hundreds of millions of pounds... Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:29:35 uk biobank,illumina,wellcome sanger,whole genome sequencing,genetic code,half a million genomes,pharmaceutical companies //www.silkstaq.com/sites/default/files/media/podcasts/episodes/guid/s7cTxKbYjtnY The Dog Show 78//www.silkstaq.com/podcasts/naked-genetics/dog-show Sat, 14 Sep 2019 05:27:49 +0100 Dogs with flat faces often struggle to breathe. What's going on in their genes? Plus, we sequence a puppy... It's a doggy dog world... in this episode we're talking pugs, bulldogs, and French bulldogs. They've all been bred for flat faces, but their airways haven't shrunk alongside their skulls - meaning that they often struggle to breathe. How has this happened? After evolving for millions of years, why are their airways literally too big to fit into their heads? Have they been betrayed by their own genes? Naked Genetics is on the case. Plus, the origin of puppy dog eyes, and we sequence the genome of Bruce the black lab puppy... Like this podcast? Please help us by supporting the Naked Scientists It's a doggy dog world... in this episode we're talking pugs, bulldogs, and French bulldogs. They've all been bred for flat faces, but their airways haven't shrunk alongside their skulls - meaning that they often struggle to breathe. How has this happened? After evolving for millions of years, why are their airways literally too big to fit into their heads? Have they been betrayed by their own genes? Naked Genetics is on the case. Plus, the origin of puppy dog eyes, and we sequence the genome of Bruce the black lab puppy... Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:30:52 dogs,puppies,Bruce,illumina,brachycephaly,brachycephalic obstructive airway syndrome,dog genetics,dog genes,sequencing a dog,sequencing a puppy //www.silkstaq.com/sites/default/files/media/podcasts/episodes/guid/aKg9ec3QPtzN Mendel's Trick 77//www.silkstaq.com/podcasts/naked-genetics/mendels-trick Wed, 14 Aug 2019 05:10:53 +0100 Time to go back to the monk who started at all. But all is not as it seems... Naked Genetics is back with new episodes every month! Today we're taking a step back. Where does genetics actually come from? How did we get to today's world of genome sequences and gene editing? It all started with a 19th-Century monk, working in his garden - but who was he really, and how did it take thirty years for him to be recognised? If you think you know this story, you might be surprised. Like this podcast? Please help us by supporting the Naked Scientists Naked Genetics is back with new episodes every month! Today we're taking a step back. Where does genetics actually come from? How did we get to today's world of genome sequences and gene editing? It all started with a 19th-Century monk, working in his garden - but who was he really, and how did it take thirty years for him to be recognised? If you think you know this story, you might be surprised. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:30:02 Gregor Mendel,father of modern genetics,founder of genetics,birth of genetics //www.silkstaq.com/guid/Naked_Genetics_19.08.14.mp3 Decoding a Mammoth with George Church 76//www.silkstaq.com/podcasts/naked-genetics/decoding-mammoth-george-church Sun, 24 Mar 2019 00:00:00 +0000 Join Harvard DNA pioneer George Church and Chris Smith in conversation as they discuss gene cloning, DNA sequencing, decoding the mammoth genome, the risks posed by fossil viruses lurking in extinct genomes, the prospects of... Join Harvard DNA pioneer George Church and Chris Smith in conversation as they discuss gene cloning, DNA sequencing, decoding the mammoth genome, the risks posed by fossil viruses lurking in extinct genomes, the prospects of xenotransplantation and safety of gene therapy, and the risks of human CRISPR. The discussion was recorded on March 15th, live in front of a studio audience at the Hello Tomorrow Summit, in Paris, 2019... Like this podcast? Please help us by supporting the Naked Scientists Join Harvard DNA pioneer George Church and Chris Smith in conversation as they discuss gene cloning, DNA sequencing, decoding the mammoth genome, the risks posed by fossil viruses lurking in extinct genomes, the prospects of xenotransplantation and safety of gene therapy, and the risks of human CRISPR. The discussion was recorded on March 15th, live in front of a studio audience at the Hello Tomorrow Summit, in Paris, 2019... Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:30:51 george church,chris smith,hello tomorrow,genome editing,genome sequencing,ancient dna,mammoth dna sequence,gene editing,CRISPR,bioethics,xenotransplantation,endogenous retroviruses //www.silkstaq.com/guid/GEORGE-CHURCH_in_conversation.mp3 The CRISPR baby controversy 75//www.silkstaq.com/podcasts/naked-genetics/crispr-baby-controversy Fri, 21 Dec 2018 00:00:00 +0000 In November, He Jiankui claimed that two genetically engineered children have been born. Did he really do it? And if so, what are the ramifications for the babies and for the field? Georgia Mills explores the controversy in a special... In November, He Jiankui claimed that two genetically engineered children have been born. Did he really do it? And if so, what are the ramifications for the babies and for the field? Georgia Mills explores the controversy in a special edition of Naked Genetics. Like this podcast? Please help us by supporting the Naked Scientists In November, He Jiankui claimed that two genetically engineered children have been born. Did he really do it? And if so, what are the ramifications for the babies and for the field? Georgia Mills explores the controversy in a special edition of Naked Genetics. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:28:04 crispr,babies,gm babies,lulu,nana,he jiankui,crispr babies,genetically modified babies //www.silkstaq.com/guid/Naked_Genetics_18.12.21.mp3 The future of forensic genetics 74//www.silkstaq.com/podcasts/naked-genetics/future-forensic-genetics Sat, 14 Apr 2018 00:00:00 +0100 We're returning to the scene of the crime with another look at the latest techniques in the world of forensic genetics - can we really predict physical features or even ethnicity from your DNA, and what does this mean for our criminal... We're returning to the scene of the crime with another look at the latest techniques in the world of forensic genetics - can we really predict physical features or even ethnicity from your DNA, and what does this mean for our criminal justice system? Plus, is the 'CSI effect' real? And our gene of the month would be more at home at a rave than a lab. Like this podcast? Please help us by supporting the Naked Scientists We're returning to the scene of the crime with another look at the latest techniques in the world of forensic genetics - can we really predict physical features or even ethnicity from your DNA, and what does this mean for our criminal justice system? Plus, is the 'CSI effect' real? And our gene of the month would be more at home at a rave than a lab. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:32:34 naked scientists, Naked genetics, genes, DNA, forensic, crime, justice, CSI, ethics, face, epigenetics, zebrafish, techno //www.silkstaq.com/guid/Naked_Genetics_18.04.14.mp3 A Festival of Genomics 73//www.silkstaq.com/podcasts/naked-genetics/festival-genomics Wed, 14 Mar 2018 00:00:00 +0000 我们一个节日——但在你担心abo血型ut where your tent and wellies are, it's the Festival of Genomics, held at a clean and dry conference centre in London rather than a muddy field full of rock bands and dodgy burgers. Plus,... 我们一个节日——但在你担心abo血型ut where your tent and wellies are, it's the Festival of Genomics, held at a clean and dry conference centre in London rather than a muddy field full of rock bands and dodgy burgers. Plus, what does the public really think of genetic technology? And a fiery gene of the month. This is the Naked Genetics podcast for March 2018, brought to you in association with The Genetics Society. Like this podcast? Please help us by supporting the Naked Scientists 我们一个节日——但在你担心abo血型ut where your tent and wellies are, it's the Festival of Genomics, held at a clean and dry conference centre in London rather than a muddy field full of rock bands and dodgy burgers. Plus, what does the public really think of genetic technology? And a fiery gene of the month. This is the Naked Genetics podcast for March 2018, brought to you in association with The Genetics Society. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:39:48 naked scientists, Genes, DNA, genetics, genomics, sequencing, genomes, NHS, blockchain, public, economics, diversity, dragon, hobbit, smaug //www.silkstaq.com/guid/Naked_Genetics_18.03.14.mp3 Crime scene genes 72//www.silkstaq.com/podcasts/naked-genetics/crime-scene-genes Wed, 14 Feb 2018 00:00:00 +0000 It's CSI Naked Genetics, as we find out how genetic technology is used to solve crimes.... It's CSI Naked Genetics, as we find out how genetic technology is used to solve crimes. Like this podcast? Please help us by supporting the Naked Scientists It's CSI Naked Genetics, as we find out how genetic technology is used to solve crimes. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:31:22 naked scientists, naked genetics, genes, DNA, genetics, forensic science, crime, blood, evidence, police, giant, fruit fly, law, innocence, guilty //www.silkstaq.com/guid/Naked_Genetics_18.02.14.mp3 Back to the womb 71//www.silkstaq.com/podcasts/naked-genetics/back-womb Sun, 14 Jan 2018 00:00:00 +0000 我们去旅行回到子宫之前,鳍d out about early development. Plus, the importance of placentas, why the age of your womb rather than your eggs matters, and a video game-inspired gene of the month. ... 我们去旅行回到子宫之前,鳍d out about early development. Plus, the importance of placentas, why the age of your womb rather than your eggs matters, and a video game-inspired gene of the month. Like this podcast? Please help us by supporting the Naked Scientists 我们去旅行回到子宫之前,鳍d out about early development. Plus, the importance of placentas, why the age of your womb rather than your eggs matters, and a video game-inspired gene of the month. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:34:58 naked scientists, naked genetics, Genes, genetics, DNA, development, womb, placenta, fertility, eggs, baby, fetus, embryo, epigenetics, oocytes, ips cells, stem cells, muscle, zelda, fruit fly //www.silkstaq.com/guid/Naked_Genetics_18.01.14.mp3 The future of genomic medicine 70//www.silkstaq.com/podcasts/naked-genetics/future-genomic-medicine Thu, 14 Dec 2017 00:00:00 +0000 This month we're finding out how genetic advances are shaping the future of healthcare at the Genetics Society autumn meeting. Plus, signposts for bees and an operatic gene of the month.... This month we're finding out how genetic advances are shaping the future of healthcare at the Genetics Society autumn meeting. Plus, signposts for bees and an operatic gene of the month. Like this podcast? Please help us by supporting the Naked Scientists This month we're finding out how genetic advances are shaping the future of healthcare at the Genetics Society autumn meeting. Plus, signposts for bees and an operatic gene of the month. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:32:50 naked scientists, Naked genetics, genes, DNA, genomics, healthcare, CRISPR, gene therapy, plants, snapdragons, bees, Pavarotti, opera, drosophila, data //www.silkstaq.com/guid/Naked_Genetics_17.12.14.mp3 Matchmaking at the zoo 69//www.silkstaq.com/podcasts/naked-genetics/matchmaking-zoo Tue, 14 Nov 2017 00:00:00 +0000 This month we're off to the zoo to meet some lovelorn laughing thrushes, endangered snails, and the Cilla Black of Sumatran Tigers. Plus, a sneak preview of this year's Genetics Society JBS Haldane lecture, and a gene of the month that... This month we're off to the zoo to meet some lovelorn laughing thrushes, endangered snails, and the Cilla Black of Sumatran Tigers. Plus, a sneak preview of this year's Genetics Society JBS Haldane lecture, and a gene of the month that likes a tipple. Like this podcast? Please help us by supporting the Naked Scientists This month we're off to the zoo to meet some lovelorn laughing thrushes, endangered snails, and the Cilla Black of Sumatran Tigers. Plus, a sneak preview of this year's Genetics Society JBS Haldane lecture, and a gene of the month that likes a tipple. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:35:22 naked scientists, Naked Genetics, genes, animals, tiger, snail, bird, endangered, conservation, environment, snapdragon, plant, communication, alcohol, hangover, fruit fly, DNA, zoo, tropical, diversity, genetics //www.silkstaq.com/guid/Naked_Genetics_17.11.14.mp3 Evolution's luxury item 68//www.silkstaq.com/podcasts/naked-genetics/evolutions-luxury-item Sat, 14 Oct 2017 00:00:00 +0100 You're a mammal. I'm a mammal. Your pet cat or dog is a mammal, as are whales, lemurs, pandas and polar bears. But what exactly is a mammal, and what can our genes tell us about our evolution? Plus, school students take on the whipworm... You're a mammal. I'm a mammal. Your pet cat or dog is a mammal, as are whales, lemurs, pandas and polar bears. But what exactly is a mammal, and what can our genes tell us about our evolution? Plus, school students take on the whipworm genome, the surprising genetic diversity of Papua New Guinea, and a gene of the month that's up all night. Like this podcast? Please help us by supporting the Naked Scientists You're a mammal. I'm a mammal. Your pet cat or dog is a mammal, as are whales, lemurs, pandas and polar bears. But what exactly is a mammal, and what can our genes tell us about our evolution? Plus, school students take on the whipworm genome, the surprising genetic diversity of Papua New Guinea, and a gene of the month that's up all night. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:32:22 naked scientists, naked genetics, mammal, animal, genetics, evolution, biology, whipworm, genetics, genomics, annotation, parasite, Papua New Guinea, diversity, language, insomnia, sleep, insomniac, gene editing, human embryo, genetic engineering, CRI //www.silkstaq.com/guid/Naked_Genetics_17.10.14.mp3 Exposing the contents of your genes 67//www.silkstaq.com/podcasts/naked-genetics/exposing-contents-your-genes Thu, 14 Sep 2017 00:00:00 +0100 Would you ever consider donating your genome to research? We meet a man who has, and find out why. Plus, we get our hands dirty in the search for new antibiotics, take a look at the ethics of human gene editing, and our gene of the month is... Would you ever consider donating your genome to research? We meet a man who has, and find out why. Plus, we get our hands dirty in the search for new antibiotics, take a look at the ethics of human gene editing, and our gene of the month is getting ahead in life. Like this podcast? Please help us by supporting the Naked Scientists Would you ever consider donating your genome to research? We meet a man who has, and find out why. Plus, we get our hands dirty in the search for new antibiotics, take a look at the ethics of human gene editing, and our gene of the month is getting ahead in life. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:31:23 naked scientists, genes, genetics, DNA, donation, consent, ethics, CRISPR, gene editing, human, antibiotics, soil, Cerberus, head, bees, microRNA, viruses, HHV, herpes, //www.silkstaq.com/guid/Naked_Genetics_17.09.14.mp3 Store, write, edit 66//www.silkstaq.com/podcasts/naked-genetics/store-write-edit Mon, 14 Aug 2017 00:00:00 +0100 As scientists announce that they have used CRISPR technology to fix a faulty gene in a human embryo - not for the first time, but more accurately than ever before - we take a look at storing, writing and editing in DNA. Plus, our gene of... As scientists announce that they have used CRISPR technology to fix a faulty gene in a human embryo - not for the first time, but more accurately than ever before - we take a look at storing, writing and editing in DNA. Plus, our gene of the month is all ears. Like this podcast? Please help us by supporting the Naked Scientists As scientists announce that they have used CRISPR technology to fix a faulty gene in a human embryo - not for the first time, but more accurately than ever before - we take a look at storing, writing and editing in DNA. Plus, our gene of the month is all ears. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:34:34 naked scientists, naked genetics, genes, DNA, genetics, embryos, CRISPR, gene therapy, Spock, heart, storage, code, gene editing, human embryos //www.silkstaq.com/guid/Naked_Genetics_17.08.14.mp3 Genes and dementia 65//www.silkstaq.com/podcasts/naked-genetics/genes-and-dementia Fri, 14 Jul 2017 00:00:00 +0100 This month we're taking a look at the role that genes play in dementia, and finding out how researchers are using this knowledge to develop urgently-needed treatments. Plus, a big release of big data from the UK Biobank, and our gene of the... This month we're taking a look at the role that genes play in dementia, and finding out how researchers are using this knowledge to develop urgently-needed treatments. Plus, a big release of big data from the UK Biobank, and our gene of the month is an expert swordsman. Like this podcast? Please help us by supporting the Naked Scientists This month we're taking a look at the role that genes play in dementia, and finding out how researchers are using this knowledge to develop urgently-needed treatments. Plus, a big release of big data from the UK Biobank, and our gene of the month is an expert swordsman. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:29:52 naked scientists, genes, DNA, genetics, dementia, brain, alzheimer's, biobank, health, samurai, fruit fly, neuron, proteins, proteomics //www.silkstaq.com/guid/Naked_Genetics_17.07.14.mp3 Bees, tress and 3-D genes 64//www.silkstaq.com/podcasts/naked-genetics/trees-bees-and-3-d-genes Wed, 14 Jun 2017 00:00:00 +0100 This month we're literally getting inside our genes, as we explore chromosomes through a 3-dimensional virtual reality art, music and science project. Plus, researchers are turning to bees, trees and more in search of new genetic systems,... This month we're literally getting inside our genes, as we explore chromosomes through a 3-dimensional virtual reality art, music and science project. Plus, researchers are turning to bees, trees and more in search of new genetic systems, and our gene of the month has been around for a while. Like this podcast? Please help us by supporting the Naked Scientists This month we're literally getting inside our genes, as we explore chromosomes through a 3-dimensional virtual reality art, music and science project. Plus, researchers are turning to bees, trees and more in search of new genetic systems, and our gene of the month has been around for a while. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:34:09 naked scientists, Genes, DNA, genetics, virtual reality, VR, gaming, chromosome, structure, 3-D, bees, trees, neonicotinoids, ash dieback, methuselah,music, art //www.silkstaq.com/guid/Naked_Genetics_17.06.14.mp3 Tackling tumours, curing cancer 63//www.silkstaq.com/podcasts/naked-genetics/tackling-tumours-curing-cancer Sun, 14 May 2017 00:00:00 +0100 This month we're zooming in on cancer, finding out how researchers are tackling tumours in unprecedented detail. Plus, our gene of the month is the guardian of your genome, rather than the galaxy. ... This month we're zooming in on cancer, finding out how researchers are tackling tumours in unprecedented detail. Plus, our gene of the month is the guardian of your genome, rather than the galaxy. Like this podcast? Please help us by supporting the Naked Scientists This month we're zooming in on cancer, finding out how researchers are tackling tumours in unprecedented detail. Plus, our gene of the month is the guardian of your genome, rather than the galaxy. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:44:07 naked scientists, naked genetics, genes, genetics, DNA, cancer, chemotherapy, treatment, personalised medicine, p53, tumours, ovarian //www.silkstaq.com/guid/Naked_Genetics_17.05.14.mp3 Battle of the sexes 62//www.silkstaq.com/podcasts/naked-genetics/battle-sexes Fri, 14 Apr 2017 00:00:00 +0100 We might joke about the battle of the sexes, but it turns out that this is actually true - at least for a hundred or so imprinted genes. Plus, what opossums can teach us about sex, reporting back from a very special scientific meeting, and... We might joke about the battle of the sexes, but it turns out that this is actually true - at least for a hundred or so imprinted genes. Plus, what opossums can teach us about sex, reporting back from a very special scientific meeting, and a superhero-styled gene of the month. Like this podcast? Please help us by supporting the Naked Scientists We might joke about the battle of the sexes, but it turns out that this is actually true - at least for a hundred or so imprinted genes. Plus, what opossums can teach us about sex, reporting back from a very special scientific meeting, and a superhero-styled gene of the month. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:31:51 naked scientists, genes, DNA, imprinting, genetics, opossum, sex, turtle, ageing, protein, Spiderman //www.silkstaq.com/guid/Naked_Genetics_17.04.14.mp3 Putting genomics to work 61//www.silkstaq.com/podcasts/naked-genetics/putting-genomics-work Wed, 15 Mar 2017 00:00:00 +0000 DNA测序革命提供了密苏里州re data about genomes from all kinds of species, from humans to bacteria. But how do we make sense of it all? Who gets their hands on it? And how do we use it to benefit patients? We meet... DNA测序革命提供了密苏里州re data about genomes from all kinds of species, from humans to bacteria. But how do we make sense of it all? Who gets their hands on it? And how do we use it to benefit patients? We meet the scientists developing new computer tools to analyse and democratise global genomics. Plus, how your partner's genes affect you - assuming you're a mouse - and a shrunken gene of the month. Like this podcast? Please help us by supporting the Naked Scientists DNA测序革命提供了密苏里州re data about genomes from all kinds of species, from humans to bacteria. But how do we make sense of it all? Who gets their hands on it? And how do we use it to benefit patients? We meet the scientists developing new computer tools to analyse and democratise global genomics. Plus, how your partner's genes affect you - assuming you're a mouse - and a shrunken gene of the month. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:29:03 naked scientists, Naked genetics, genes, DNA, genetics, computer, antibiotic resistance, social, India, genomics, global, clinical genetics, hereditary //www.silkstaq.com/guid/Naked_Genetics_17.03.14.mp3 Science and the single cell 60//www.silkstaq.com/podcasts/naked-genetics/science-and-single-cell Tue, 14 Feb 2017 00:00:00 +0000 Our bodies are made up of trillions of cells - but these aren't mere biological building blocks, as inert as bricks. They're constantly communicating and changing. So how do scientists measure this? Plus, you can now take part in an... Our bodies are made up of trillions of cells - but these aren't mere biological building blocks, as inert as bricks. They're constantly communicating and changing. So how do scientists measure this? Plus, you can now take part in an international survey about genetics knowledge, a GIANT study throws up new genes linked to height, and a romantic gene of the month. Like this podcast? Please help us by supporting the Naked Scientists Our bodies are made up of trillions of cells - but these aren't mere biological building blocks, as inert as bricks. They're constantly communicating and changing. So how do scientists measure this? Plus, you can now take part in an international survey about genetics knowledge, a GIANT study throws up new genes linked to height, and a romantic gene of the month. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:30:04 naked scientists, genes, DNA, cells, height, development, love, Valentine //www.silkstaq.com/guid/Naked_Genetics_17.02.14.mp3 Genes, laws and Brexit 59//www.silkstaq.com/podcasts/naked-genetics/genes-laws-and-brexit Sat, 14 Jan 2017 00:00:00 +0000 We hear a lot about genetic modification and how it's being used to improve agriculture. But who decides whether modified crops can be grown? Do new gene editing techniques like CRISPR count as GM? And what happens to these regulations when... We hear a lot about genetic modification and how it's being used to improve agriculture. But who decides whether modified crops can be grown? Do new gene editing techniques like CRISPR count as GM? And what happens to these regulations when the UK leaves the EU? Plus, our gene of the month comes with a tale behind it. Like this podcast? Please help us by supporting the Naked Scientists We hear a lot about genetic modification and how it's being used to improve agriculture. But who decides whether modified crops can be grown? Do new gene editing techniques like CRISPR count as GM? And what happens to these regulations when the UK leaves the EU? Plus, our gene of the month comes with a tale behind it. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:29:16 naked scientists, genetics, legislation, EU, UK, Brexit, genes, gene editing, GM food, GM crops, genetic modification, retroviruses, dachshund //www.silkstaq.com/guid/Naked_Genetics_17.01.14.mp3 All human life is here 58//www.silkstaq.com/podcasts/naked-genetics/all-human-life-here Wed, 14 Dec 2016 00:00:00 +0000 Human evolution is complicated, but you're only here because your ancestors got lucky The story of human evolution is long and complicated, but the simple truth is - you're only here because your ancestors got lucky. Plus, we wind the clock back to the very start of human life, and discover how new research is pushing back the frontiers of human embryology. Plus a suitably festive gene of the month. This is the Naked Genetics podcast for December 2016 with me, Dr Kat Arney, brought to you in association with The Genetics Society, online at genetics.org.uk. Like this podcast? Please help us by supporting the Naked Scientists The story of human evolution is long and complicated, but the simple truth is - you're only here because your ancestors got lucky. Plus, we wind the clock back to the very start of human life, and discover how new research is pushing back the frontiers of human embryology. Plus a suitably festive gene of the month. This is the Naked Genetics podcast for December 2016 with me, Dr Kat Arney, brought to you in association with The Genetics Society, online at genetics.org.uk. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:29:56 naked scientists, Genes, genetics, DNA, history, evolution, neanderthal, denisovan, rutherford, embryo, human, HFEA, ethics, research, gene editing, blastocyst, christmas, haemophilia //www.silkstaq.com/guid/Naked_Genetics_16.12.14.mp3 Searching for switches 57//www.silkstaq.com/podcasts/naked-genetics/searching-switches Mon, 14 Nov 2016 00:00:00 +0000 本月我们将深入探究基因族群中的垃圾me, properly called non-coding DNA. 本月我们将深入探究基因族群中的垃圾me - or, to put it more correctly - our non-coding DNA. Less than 2 per cent of the human genome contains protein-coding genes, so what does all the rest do? Like this podcast? Please help us by supporting the Naked Scientists 本月我们将深入探究基因族群中的垃圾me - or, to put it more correctly - our non-coding DNA. Less than 2 per cent of the human genome contains protein-coding genes, so what does all the rest do? Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:30:14 naked scientists, genes, DNA, genetics, evolution, mammals, mammalian, enhancers, regulation, Ciona, whale, mole rat, meeting, conference, switches, regulatory elements, bonobo, chimp, Ebola, Huntington's disease, Hallowe'en, Ouija board, Halloween //www.silkstaq.com/guid/Naked_Genetics_16.11.14.mp3 Testing, testing 56//www.silkstaq.com/podcasts/naked-genetics/testing-testing Fri, 14 Oct 2016 00:00:00 +0100 We look at gene tests claiming to reveal everything from cancer risk to sporting ability. We hear more than ever about the secrets hidden in our genes, from our risk of diseases to traits such as intelligence or even sporting ability. But can we really test for them? And just because we can, does that mean we should? Plus, an extremely popular - and extremely distracting - gene of the month. This is the Naked Genetics podcast for October 2016 with me, Dr Kat Arney, brought to you in association with The Genetics Society, online at genetics.org.uk. Like this podcast? Please help us by supporting the Naked Scientists We hear more than ever about the secrets hidden in our genes, from our risk of diseases to traits such as intelligence or even sporting ability. But can we really test for them? And just because we can, does that mean we should? Plus, an extremely popular - and extremely distracting - gene of the month. This is the Naked Genetics podcast for October 2016 with me, Dr Kat Arney, brought to you in association with The Genetics Society, online at genetics.org.uk. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:30:15 naked scientists, genes, genetics, DNA, testing, preimplantation, PGD, NIPT, down syndrome, PGS, pregnancy, baby, cancer, ovarian, breast, BRCA, screening, sport, pokemon //www.silkstaq.com/guid/Naked_Genetics_16.10.14.mp3 Hello Dolly 55//www.silkstaq.com/podcasts/naked-genetics/hello-dolly Wed, 14 Sep 2016 00:00:00 +0100 This month we're commemorating twenty years since the birth of Dolly the Sheep This month we've got a special bonus-length podcast commemorating twenty years since the birth of Dolly the Sheep, the first mammal cloned from an adult cell. Her birth changed the scientific world, and led to the development of other transformative technologies. Plus, our gene of the month is keeping a straight face. Like this podcast? Please help us by supporting the Naked Scientists This month we've got a special bonus-length podcast commemorating twenty years since the birth of Dolly the Sheep, the first mammal cloned from an adult cell. Her birth changed the scientific world, and led to the development of other transformative technologies. Plus, our gene of the month is keeping a straight face. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:41:03 naked scientists, clone, cloning, Dolly, sheep, cow, Roslin, iPS, yamanaka, wilmut, stem cell, xenotransplantation, chicken, deadpan, tissue, genes, DNA, egg, pig //www.silkstaq.com/guid/Naked_Genetics_16.09.14.mp3 40 years of selfishness 54//www.silkstaq.com/podcasts/naked-genetics/40-years-selfishness Sun, 14 Aug 2016 00:00:00 +0100 40 years ago Richard Dawkins' The Selfish Gene hit the shelves. We look back on its legacy 40 years ago Richard Dawkins' The Selfish Gene hit the shelves. We look back on how it changed the way many people think about genetics. Plus, linking nurture to nature, and a gigantic gene of the month. Like this podcast? Please help us by supporting the Naked Scientists 40 years ago Richard Dawkins' The Selfish Gene hit the shelves. We look back on how it changed the way many people think about genetics. Plus, linking nurture to nature, and a gigantic gene of the month. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:30:00 naked scientists, Naked genetics, Genes, genetics, DNA, selfish, evolution, epigenetics, pregnancy, maternal, heart, cardiomyopathy, methylation, book, selfish gene, Dawkins, Darwin //www.silkstaq.com/guid/Naked_Genetics_16.08.14.mp3 Signal to noise 53//www.silkstaq.com/podcasts/naked-genetics/signal-noise Thu, 14 Jul 2016 00:00:00 +0100 We find out how signals between cells build organisms. Building a baby is a complicated business, with millions of cells needing to work together. So how does it happen? Plus, how big data is making big strides in big genes, and our gene of the month is going round and round in circles. Like this podcast? Please help us by supporting the Naked Scientists Building a baby is a complicated business, with millions of cells needing to work together. So how does it happen? Plus, how big data is making big strides in big genes, and our gene of the month is going round and round in circles. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:30:00 naked scientists, genes, DNA, genomes, FGF, fibroblasts, signals, development, salivary glands, cancer, Dolly, sheep, cloning, roundabout //www.silkstaq.com/guid/Naked_Genetics_16.07.14.mp3 Genes for all 52//www.silkstaq.com/podcasts/naked-genetics/genes-all Tue, 14 Jun 2016 00:00:00 +0100 Is the public ready to look inside its genes? Genes, genomes and genetic technology are playing increasingly important parts in our lives, industries, food and healthcare, and at a point in the not-too-distant future we're probably going to have to grapple with at least some of the contents of our DNA. But is the public really prepared to look inside its genes? Plus, the company aiming to bring molecular biology labs for all, and our gene of the month is crunchy on the outside. This is the Naked Genetics podcast for June 2016 with me, Dr Kat Arney, brought to you in association with The Genetics Society, online at genetics.org.uk. Like this podcast? Please help us by supporting the Naked Scientists Genes, genomes and genetic technology are playing increasingly important parts in our lives, industries, food and healthcare, and at a point in the not-too-distant future we're probably going to have to grapple with at least some of the contents of our DNA. But is the public really prepared to look inside its genes? Plus, the company aiming to bring molecular biology labs for all, and our gene of the month is crunchy on the outside. This is the Naked Genetics podcast for June 2016 with me, Dr Kat Arney, brought to you in association with The Genetics Society, online at genetics.org.uk. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:30:00 naked scientists, genes, genomes, genetics, genetic counselling, armadillo, Bento, lab, X-men, //www.silkstaq.com/guid/Naked_Genetics_16.06.14.mp3 Check your compatibility 51//www.silkstaq.com/podcasts/naked-genetics/check-your-compatibility Sat, 14 May 2016 00:00:00 +0100 Your health, immune system and even love-life are governed by compatibility genes. You may not realise it, but your health, immune system and even love-life are governed by the particular set of so-called compatibility genes that you inherit. There are thousands of different variations in these genes, but why do we have such diversity and does it matter? Plus, we dig into the latest research on cancer genetics - how studying hundreds of tumour genomes might bring forward new breast cancer cures. Like this podcast? Please help us by supporting the Naked Scientists You may not realise it, but your health, immune system and even love-life are governed by the particular set of so-called compatibility genes that you inherit. There are thousands of different variations in these genes, but why do we have such diversity and does it matter? Plus, we dig into the latest research on cancer genetics - how studying hundreds of tumour genomes might bring forward new breast cancer cures. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:30:00 naked scientists, genes, genomes, genetics, immune system, compatibility, transplants, HLA, histocompatibility, cancer, breast, mutations //www.silkstaq.com/guid/Naked_Genetics_16.05.14.mp3 在你的基因是什么? 50//www.silkstaq.com/podcasts/naked-genetics/whats-your-genes Thu, 14 Apr 2016 00:00:00 +0100 What do home genetic tests really reveal? Plus, the four-legged genetics of dogs. As the costs of DNA analysis come down, we've seen the rise of direct-to-consumer genetic testing, allowing anyone to spit in a tube, pop it in the post and get a personalised readout direct to their inbox. But what do these tests actually reveal? Plus, how advertising execs can help us talk about genes, digging up the secrets in dogs genomes, and our gene of the month is totally legless. Like this podcast? Please help us by supporting the Naked Scientists As the costs of DNA analysis come down, we've seen the rise of direct-to-consumer genetic testing, allowing anyone to spit in a tube, pop it in the post and get a personalised readout direct to their inbox. But what do these tests actually reveal? Plus, how advertising execs can help us talk about genes, digging up the secrets in dogs genomes, and our gene of the month is totally legless. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:30:00 naked scientists, genes, genetics, tests, dogs, genomics, ethics, gene therapy, pregnant, VEGF, DNA //www.silkstaq.com/guid/Naked_Genetics_16.04.14.mp3 Designer genes 49//www.silkstaq.com/podcasts/naked-genetics/designer-genes Mon, 14 Mar 2016 00:00:00 +0000 Are we on the road to designer babies? Plus, we unpack the latest cancer breakthrough. The recent invention of powerful precision tools for editing the human genome - known as CRISPR, has opened up new worlds of possibilities for researchers seeking to understand how our genes work - and also those who want to permanently change the human genome for generations to come. But are we on the road to designer babies? Plus, we unpack the latest cancer breakthrough, and our gene of the month is making a terrible racket. Like this podcast? Please help us by supporting the Naked Scientists The recent invention of powerful precision tools for editing the human genome - known as CRISPR, has opened up new worlds of possibilities for researchers seeking to understand how our genes work - and also those who want to permanently change the human genome for generations to come. But are we on the road to designer babies? Plus, we unpack the latest cancer breakthrough, and our gene of the month is making a terrible racket. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:32:01 naked scientists, genetics, CRISPR, genes, engineering, cancer, immunotherapy, genomics, DNA //www.silkstaq.com/guid/Naked_Genetics_16.03.14.mp3 Crazy for CRISPR 48//www.silkstaq.com/podcasts/naked-genetics/crazy-crispr Sun, 14 Feb 2016 00:00:00 +0000 CRISPR is a precision set of genome editing tools with big implications for human health It's the hottest new biotechnology technique to hit the headlines since well, since ever. CRISPR is a precision set of genome editing tools enabling scientists to cut and paste together DNA in any organism, exactly how they want - and the implications for human health, and even humanity, are huge. Plus, linking genetics to lifestyle, and our gene of the month is black and white and very cute. Like this podcast? Please help us by supporting the Naked Scientists It's the hottest new biotechnology technique to hit the headlines since well, since ever. CRISPR is a precision set of genome editing tools enabling scientists to cut and paste together DNA in any organism, exactly how they want - and the implications for human health, and even humanity, are huge. Plus, linking genetics to lifestyle, and our gene of the month is black and white and very cute. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:30:00 naked scientists, genes, genetics, CRISPR, editing, designer babies, cystic fibrosis, GWAS, genome wide association study, lifestyle, DNA, ethics //www.silkstaq.com/guid/Naked_Genetics_16.02.14.mp3 Naked Genetics 47 47//www.silkstaq.com/podcasts/naked-genetics/naked-genetics-47 Thu, 14 Jan 2016 00:00:00 +0000 This month we bring you a bumper edition full of our favourite bits from the past 4 years. This month we bring you a bumper edition, packed full of all our favourite bits from the past four years. Like this podcast? Please help us by supporting the Naked Scientists This month we bring you a bumper edition, packed full of all our favourite bits from the past four years. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:57:45 赤裸裸的科学家、基因、DNA、遗传学、土耳其,sex, bedbugs, evolution, Viking, history, genealogy, mice, rage, alcohol, drunk, hangover, music, smell, Callipyge, astronaut //www.silkstaq.com/guid/Naked_Genetics_16.01.14.mp3 Naked Genetics 46 46//www.silkstaq.com/podcasts/naked-genetics/naked-genetics-46 Mon, 14 Dec 2015 00:00:00 +0000 Synthetic biology - engineering life - is set to revolutionise the world, but how? Synthetic biology - engineering life - is set to revolutionise the world, but how? We'll be hearing about some of the most exciting applications for synthetic biology, and how it's being commercialised. Plus, our gene of the month has got itself all in a twist. Like this podcast? Please help us by supporting the Naked Scientists Synthetic biology - engineering life - is set to revolutionise the world, but how? We'll be hearing about some of the most exciting applications for synthetic biology, and how it's being commercialised. Plus, our gene of the month has got itself all in a twist. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:30:00 Nanotech,Engineering,biology,building,build,Genetics,Biology,hacking,CEO,synthetic biology,2015,hacking,fruit fly,sang,wellcome trust,evolution.,elderly,naked scientists //www.silkstaq.com/guid/Naked_Genetics_15.14.12.mp3 Why don't elephants get cancer? 45//www.silkstaq.com/podcasts/naked-genetics/why-dont-elephants-get-cancer Sat, 14 Nov 2015 00:00:00 +0000 Elephants are made up of many more cells than humans, but don't get cancer. Why? Animals like elephants and whales are made up of many more cells than a human, or a mouse, and they live far longer. Yet they hardly ever get cancer - and the big question is why? Plus, revolutions in genetics, and a magical gene of the month. Like this podcast? Please help us by supporting the Naked Scientists Animals like elephants and whales are made up of many more cells than a human, or a mouse, and they live far longer. Yet they hardly ever get cancer - and the big question is why? Plus, revolutions in genetics, and a magical gene of the month. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:30:00 naked scientists, genes, genetics, evolution, cancer, animals, elephants //www.silkstaq.com/guid/Naked_Genetics_15.11.14.mp3 Engineering life 44//www.silkstaq.com/podcasts/naked-genetics/engineering-life Wed, 14 Oct 2015 00:00:00 +0100 Imagine designing bacteria that can do whatever you want - this is synthetic biology. Imagine designing bacteria that can do whatever you want - from cleaning up oil spills to churning out the latest cancer treatments - ordering the biological parts online and building it in a couple of weeks. This is no longer the stuff of dreams, but the reality of synthetic biology. Plus, tracing European genes, how parasites manipulate our immune systems, I take part in a research project to find out if sociability is in my genes, and our gene of the month is looking for wedded bliss. Like this podcast? Please help us by supporting the Naked Scientists Imagine designing bacteria that can do whatever you want - from cleaning up oil spills to churning out the latest cancer treatments - ordering the biological parts online and building it in a couple of weeks. This is no longer the stuff of dreams, but the reality of synthetic biology. Plus, tracing European genes, how parasites manipulate our immune systems, I take part in a research project to find out if sociability is in my genes, and our gene of the month is looking for wedded bliss. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:30:00 naked scientists, genes, Dna, genetics, synthetic biology, parasites, RNA, exosomes, //www.silkstaq.com/guid/Naked_Genetics_15.10.14.mp3 Hundreds and Thousands 43//www.silkstaq.com/podcasts/naked-genetics/hundreds-and-thousands Mon, 14 Sep 2015 00:00:00 +0100 To figure out which genes are linked to diseases, researchers have to go large. When it comes to figuring out which genes and genetic variations are linked to particular traits and diseases, there's only one way to do it, and that's to go large, with cohort studies involving hundreds or even thousands of volunteers. We meet the Born In Bradford bunch, a Canadian cohort, and more than a few pairs of twins. Plus, oh my God, they killed our gene of the month! Like this podcast? Please help us by supporting the Naked Scientists When it comes to figuring out which genes and genetic variations are linked to particular traits and diseases, there's only one way to do it, and that's to go large, with cohort studies involving hundreds or even thousands of volunteers. We meet the Born In Bradford bunch, a Canadian cohort, and more than a few pairs of twins. Plus, oh my God, they killed our gene of the month! Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:30:00 naked scientists, genes, DNA, genetics, twins, Canada, Bradford, cohort, epidemiology, disease, cousins, marriage, Kenny, asthma, epigenetics, allergies //www.silkstaq.com/guid/Naked_Genetics_15.09.14.mp3 Mysterious methylation 42//www.silkstaq.com/podcasts/naked-genetics/mysterious-methylation Fri, 14 Aug 2015 00:00:00 +0100 There's more to life than four letters of DNA: our genes are marked with a chemical 'tag'. There's more to life than the four letters of DNA, and our cells use a chemical tag known as DNA methylation to mark out certain parts of the genome, helping cells to remember what they're doing. And, as you might expect, it's pretty important. Plus, how your GCSE success could be encoded in your genes, an important molecular cause of autism identified, and an illuminating gene of the month. Like this podcast? Please help us by supporting the Naked Scientists There's more to life than the four letters of DNA, and our cells use a chemical tag known as DNA methylation to mark out certain parts of the genome, helping cells to remember what they're doing. And, as you might expect, it's pretty important. Plus, how your GCSE success could be encoded in your genes, an important molecular cause of autism identified, and an illuminating gene of the month. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:30:00 naked scientists, DNA, genetics, methylation, epigenetics, cancer, autism, intelligence, genes, Rett syndrome, education, lava lamp, MeCP2, //www.silkstaq.com/guid/Naked_Genetics_15.08.14.mp3 The wonderful world of epigenetics 41//www.silkstaq.com/podcasts/naked-genetics/wonderful-world-epigenetics Tue, 14 Jul 2015 00:00:00 +0100 How do different types of cells know which genes to use? The answer lies in epigenetics. Genes are the instructions that tell our cells what to do, but how do different types of cells know which genes to switch on or off at the right time? The solution lies in epigenetics - the molecular bells and whistles that act on top of our DNA to control gene activity. Plus, a new gene involved in severe obesity, and a mythical gene of the month. Like this podcast? Please help us by supporting the Naked Scientists Genes are the instructions that tell our cells what to do, but how do different types of cells know which genes to switch on or off at the right time? The solution lies in epigenetics - the molecular bells and whistles that act on top of our DNA to control gene activity. Plus, a new gene involved in severe obesity, and a mythical gene of the month. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:30:00 naked scientists, genetics, DNA, RNA, epigenetics, histones, disease, obesity, diversity //www.silkstaq.com/guid/Naked_Genetics_15.07.14.mp3 Breeding a better cow 40//www.silkstaq.com/podcasts/naked-genetics/breeding-better-cow Sun, 14 Jun 2015 00:00:00 +0100 For centuries, enthusiastic breeders have selected plants or animals with desirable traits For centuries, breeders have been selecting plants and animals with desirable genetic traits. So how have some of these changes come about, and where will new genetic technologies take our food in the future? Like this podcast? Please help us by supporting the Naked Scientists For centuries, breeders have been selecting plants and animals with desirable genetic traits. So how have some of these changes come about, and where will new genetic technologies take our food in the future? Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:30:00 naked scientists, plants, cows, chickens, food, GMO, breeding, genetics, viagra, malaria, spaghetti, fruit fly, alzheimer's, wheat, genetics, genes, DNA //www.silkstaq.com/guid/Naked_Genetics_15.06.14.mp3 The story of maize 39//www.silkstaq.com/podcasts/naked-genetics/story-maize Thu, 14 May 2015 00:00:00 +0100 你可能没有意识到,但你吃的所有食物has been genetically altered over time. 你可能没有意识到,但你吃的所有食物has been genetically altered over time by plant and animal breeders, capturing advantageous traits to grow more nutritious and easy-to-farm foods as efficiently and healthily as possible. Maize, or corn as it's often know, is a prime example of this change. Plus, is attractiveness to mosquitoes in your genes? And our gene of the month is small but significant. Like this podcast? Please help us by supporting the Naked Scientists 你可能没有意识到,但你吃的所有食物has been genetically altered over time by plant and animal breeders, capturing advantageous traits to grow more nutritious and easy-to-farm foods as efficiently and healthily as possible. Maize, or corn as it's often know, is a prime example of this change. Plus, is attractiveness to mosquitoes in your genes? And our gene of the month is small but significant. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:30:00 maize,the,story,Plants,of,to,Food,Genetics,faulkes,naked mole rat,DJ,selective breeding,logan,dengue fever,gm,GMO,genetically modified,naked scientists //www.silkstaq.com/guid/Naked_Genetics_15.05.14.mp3 Patenting and preserving genes 38//www.silkstaq.com/podcasts/naked-genetics/patenting-and-preserving-genes Tue, 14 Apr 2015 00:00:00 +0100 Guarding the genes in our crops is vital to ensure food for the future. There are few things in life as important as the food we eat, but making sure that we guard the genes in our crops for the future is just as important. Plus, we take a look at some of the intellectual property issues surrounding our food, learn squid's surprising secret, and our gene of the month might be a mayor. Like this podcast? Please help us by supporting the Naked Scientists There are few things in life as important as the food we eat, but making sure that we guard the genes in our crops for the future is just as important. Plus, we take a look at some of the intellectual property issues surrounding our food, learn squid's surprising secret, and our gene of the month might be a mayor. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:30:00 naked scientists, genes, DNA, crops, patents, GMO, vegetables, fruit, squid, British, genetics, naked genetics, life, CRISPR, history, Boris //www.silkstaq.com/guid/Naked_Genetics_15.04.14.mp3 A hundred thousand genomes 37//www.silkstaq.com/podcasts/naked-genetics/hundred-thousand-genomes Sat, 14 Mar 2015 00:00:00 +0000 We look at the UK government's plan to sequence the genomes of 100,000 people Over the past year the Government has unveiled an audacious programme under the banner of Genomics England, aiming to sequence the genomes of 100,000 people affected by cancer and rare genetic diseases. We take a look at some of the practical and ethical issues around the project. Plus, our gene of the month comes from the land of the forever young. Like this podcast? Please help us by supporting the Naked Scientists Over the past year the Government has unveiled an audacious programme under the banner of Genomics England, aiming to sequence the genomes of 100,000 people affected by cancer and rare genetic diseases. We take a look at some of the practical and ethical issues around the project. Plus, our gene of the month comes from the land of the forever young. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:30:00 naked scientists, science, genetics, DNA, genomes, hundred thousand genomes, genomics England, ethics, wheat, hessian fly, peanut allergy, food allergy, cancer, rare diseases, Nanog, stem cells //www.silkstaq.com/guid/Naked_Genetics_15.03.14.mp3 Genetically Modified plants 36//www.silkstaq.com/podcasts/naked-genetics/genetically-modified-plants Sat, 14 Feb 2015 00:00:00 +0000 Genetically modified, or GM, crops are a hot topic. But what's the science behind the hype Genetically modified, or GM, crops are a hot topic. Some people are deeply suspicious of the technology while others see it as an effective and efficient way of generating bountiful, healthier harvests. Plus, purple tomatoes, a giant of a gene involved in heart disease, and what's in a name? We take a look at the naming of genes. Like this podcast? Please help us by supporting the Naked Scientists Genetically modified, or GM, crops are a hot topic. Some people are deeply suspicious of the technology while others see it as an effective and efficient way of generating bountiful, healthier harvests. Plus, purple tomatoes, a giant of a gene involved in heart disease, and what's in a name? We take a look at the naming of genes. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:30:00 naked scientists, genes, DNA, genetics, GM, GMO, genetically modified, crops, food, plants, tomatoes, heart, Titin //www.silkstaq.com/guid/Naked_Genetics_15.02.14.MP3 Clever mice and drunken flies 35//www.silkstaq.com/podcasts/naked-genetics/clever-mice-and-drunken-flies Wed, 14 Jan 2015 00:00:00 +0000 How do mice learn tasks like playing the piano? And why do flies drink after a hangover? How do we learn complex tasks like playing the piano? Why can we remember things better after a good night's sleep? And why do people - and fruit flies - drink again after the hangover from hell? The answers are all in your genes. Plus, why large-scale searches for so-called "genes for schizophrenia" and other psychiatric diseases are turning out to be trickier than we thought, and a gene of the month with a touch of Scottish - or maybe Hollywood - spirit. Like this podcast? Please help us by supporting the Naked Scientists How do we learn complex tasks like playing the piano? Why can we remember things better after a good night's sleep? And why do people - and fruit flies - drink again after the hangover from hell? The answers are all in your genes. Plus, why large-scale searches for so-called "genes for schizophrenia" and other psychiatric diseases are turning out to be trickier than we thought, and a gene of the month with a touch of Scottish - or maybe Hollywood - spirit. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:30:00 naked scientists, genetics, genes, learning, sleep, alcohol, memory, brain //www.silkstaq.com/guid/Naked_Genetics_15.01.14.mp3 Searching for the engram 34//www.silkstaq.com/podcasts/naked-genetics/searching-engram Sun, 14 Dec 2014 00:00:00 +0000 Scientists are getting close to finding the engram, where memories are stored in the brain For many years scientists have been searching for the mysterious engram - the place in the brain where memories are kept. And thanks to advances in genetics and neurobiology, it looks like they're now getting close to finding it. Plus, contagious cancers in dogs and devils, and our gene of the month prefers the cold. Like this podcast? Please help us by supporting the Naked Scientists For many years scientists have been searching for the mysterious engram - the place in the brain where memories are kept. And thanks to advances in genetics and neurobiology, it looks like they're now getting close to finding it. Plus, contagious cancers in dogs and devils, and our gene of the month prefers the cold. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:30:00 naked scientists, genetics, brain, memory, learning, gene, Tasmanian devils, cancer, dogs, canine, tumour, genes, DNA //www.silkstaq.com/guid/Naked_Genetics_14.12.14.mp3 Targeting cancer genes 33//www.silkstaq.com/podcasts/naked-genetics/targeting-cancer-genes Fri, 14 Nov 2014 00:00:00 +0000 A new generation of targeted cancer therapies are bringing hope for future cures. Every year in the UK more than 330,000 people are diagnosed with cancer. The good news is that more and more are surviving, and there's hope that the new generation of genetic research and targeted therapies will bring more cures in the future. But is cancer a cleverer enemy than we thought? Plus sealion genital cancers, and an over-excited gene of the month. Like this podcast? Please help us by supporting the Naked Scientists Every year in the UK more than 330,000 people are diagnosed with cancer. The good news is that more and more are surviving, and there's hope that the new generation of genetic research and targeted therapies will bring more cures in the future. But is cancer a cleverer enemy than we thought? Plus sealion genital cancers, and an over-excited gene of the month. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:30:00 naked scientists, DNA, genes, Genetics, Cancer, sequencing, sea lion, breast, melanoma, skin, Naked Genetics //www.silkstaq.com/guid/Naked_Genetics_14.11.14.mp3 Genes, ageing and metabolism 32//www.silkstaq.com/podcasts/naked-genetics/genes-ageing-and-metabolism Tue, 14 Oct 2014 00:00:00 +0100 Could we one day be popping pills that tweak our metabolism and make us live longer? Could we one day be popping pills that tweak our metabolism and make us live longer? It's not as far off as you might think. Plus, the cow genome goes large, bat flu flies into focus, and an untidy gene of the month. Like this podcast? Please help us by supporting the Naked Scientists Could we one day be popping pills that tweak our metabolism and make us live longer? It's not as far off as you might think. Plus, the cow genome goes large, bat flu flies into focus, and an untidy gene of the month. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:30:00 naked scientists, genes, genetics, DNA, ageing, metabolism, insulin, IGF2, cow, cattle, genome, bat, flu, virus, dog, epigenetics, neuroscience, brain, malaria //www.silkstaq.com/guid/Naked_Genetics_14.10.14.mp3 Long live our genes 31//www.silkstaq.com/podcasts/naked-genetics/long-live-our-genes Sun, 14 Sep 2014 00:00:00 +0100 We all want to live long, healthy lives - this month we find out how genetics can help. Every day we get older, and whether you're desperately resisting the march of time, or embracing the ageing process, most of us would agree we want to live as long, healthy lives as possible. We'll be finding out how genetics research can help. Plus, making fingers with Alan Turing, growing lizard tails, and a long-lived gene of the month. Like this podcast? Please help us by supporting the Naked Scientists Every day we get older, and whether you're desperately resisting the march of time, or embracing the ageing process, most of us would agree we want to live as long, healthy lives as possible. We'll be finding out how genetics research can help. Plus, making fingers with Alan Turing, growing lizard tails, and a long-lived gene of the month. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:30:00 naked scientists, science, genetics, genes, DNA, ageing, red wine, lizard, neurofibromatosis, //www.silkstaq.com/guid/Naked_Genetics_14.09.14.mp3 Genes for sore eyes 30//www.silkstaq.com/podcasts/naked-genetics/genes-sore-eyes Thu, 14 Aug 2014 00:00:00 +0100 We investigate the genetics of vision, and how researchers are helping the blind see. From the beauty of a sunset or the ugliness of war to the smile on a loved one's face, our eyes bring us all kinds of information about the world around us. now researchers are working to develop new therapies for people who have lost this precious sense. Plus, smelling elephants, marmoset twins, and an all-seeing gene of the month. Like this podcast? Please help us by supporting the Naked Scientists From the beauty of a sunset or the ugliness of war to the smile on a loved one's face, our eyes bring us all kinds of information about the world around us. now researchers are working to develop new therapies for people who have lost this precious sense. Plus, smelling elephants, marmoset twins, and an all-seeing gene of the month. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:30:00 naked scientists, genes, genetics, DNA, sight, vision, blindness, stem cells, marmoset, elephant, photoreceptor, Pax6, maths, reading //www.silkstaq.com/guid/Naked_Genetics_14.08.14.mp3 Issues for genetic testing 29//www.silkstaq.com/podcasts/naked-genetics/issues-genetic-testing Mon, 14 Jul 2014 00:00:00 +0100 New technology means more genetic testing, but what are the issues? Whether we like it or not, we're heading further along the road of genetic testing, not just for single genes but for complex diseases and even ancestry. But can the results of gene tests change our behaviour? Plus colouring crows, electric eels, gluing chromosomes and a sketchy gene of the month. Like this podcast? Please help us by supporting the Naked Scientists Whether we like it or not, we're heading further along the road of genetic testing, not just for single genes but for complex diseases and even ancestry. But can the results of gene tests change our behaviour? Plus colouring crows, electric eels, gluing chromosomes and a sketchy gene of the month. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:30:00 naked scientists, news, genetics, DNA, chromosomes, testing, genetic tests, eucalyptus, obesity, genes, naked genetics, electric eels, evolution, salmonella, food poisoning, learning, //www.silkstaq.com/guid/Naked_Genetics_14.07.14.mp3 Gene therapy - Cystic fibrosis, blindness and more 28//www.silkstaq.com/podcasts/naked-genetics/gene-therapy-cystic-fibrosis-blindness-and-more Sat, 14 Jun 2014 00:00:00 +0100 二十年前,基因疗法是一个伟大的希望佛r the future of medicine - progress has been slow but things may now be changing. 二十年前,基因疗法是一个伟大的希望佛r the future of medicine - directly tinkering with faulty genes to cure diseases, but progress has been slow. Now, things seem to be changing. Plus, silencing crickets, evolving brain and brawn, and a flowery gene of the month. Like this podcast? Please help us by supporting the Naked Scientists 二十年前,基因疗法是一个伟大的希望佛r the future of medicine - directly tinkering with faulty genes to cure diseases, but progress has been slow. Now, things seem to be changing. Plus, silencing crickets, evolving brain and brawn, and a flowery gene of the month. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:30:00 naked scientists, genes, genetics, gene therapy, CF, cystic fibrosis, sight loss blindness, HIV, crickets, evolution, grass, plant, snapdragon, DNA, chimps, brain, muscle, blind mole rat, cancer, mouse, autism //www.silkstaq.com/guid/Naked_Genetics_14.06.14.mp3 Nature, nurture and wiring the brain 27//www.silkstaq.com/podcasts/naked-genetics/nature-nurture-and-wiring-brain Wed, 14 May 2014 00:00:00 +0100 Are our brains a product of nature or nurture, and how does learning change them? The more we understand about the genetic variations that affect our brains, the more questions are raised - for example, are we a product of nature or nurture, and what should we test for? Plus, why Y loss is bad for men, the usefulness of junk DNA, and a crunchy gene of the month. Like this podcast? Please help us by supporting the Naked Scientists The more we understand about the genetic variations that affect our brains, the more questions are raised - for example, are we a product of nature or nurture, and what should we test for? Plus, why Y loss is bad for men, the usefulness of junk DNA, and a crunchy gene of the month. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:30:00 naked scientists, genes, mental health, psychiatry, schizophrenia, learning, nature, nurture, cloning, Y chromosome, health, ageing, ethics //www.silkstaq.com/guid/Naked_Genetics_14.05.14.mp3 Genes, depression and schizophrenia 26//www.silkstaq.com/podcasts/naked-genetics/genes-depression-and-schizophrenia Mon, 14 Apr 2014 00:00:00 +0100 Around one in four adults in the UK experiences mental health problems in any year, but what do we know about the genes involved? Around one in four adults in the UK experiences mental health problems in any year, and mental illness is a major problem for sufferers, their loved ones, and society. It's becoming clear that genes are involved, but what do we actually know? Plus, artificial chromosomes, autism in the womb, and a toddling little gene of the month. Like this podcast? Please help us by supporting the Naked Scientists Around one in four adults in the UK experiences mental health problems in any year, and mental illness is a major problem for sufferers, their loved ones, and society. It's becoming clear that genes are involved, but what do we actually know? Plus, artificial chromosomes, autism in the womb, and a toddling little gene of the month. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:30:00 naked scientists, news, mental health, depression, schizophrenia, psychiatry, genetics, genes, chromosome, autism, baldness, toddler, genetics //www.silkstaq.com/guid/Naked_Genetics_14.04.14.mp3 DNA damage and repair 25//www.silkstaq.com/podcasts/naked-genetics/dna-damage-and-repair 星期五,2014年3月14日就是+ 0000 We find out how DNA gets damaged and repaired. Plus liver from skin cells, DNA from ancient teeth, and a scary little gene of the month. Every second your DNA is under assault - not just from chemicals in our environment or food, but from the hurly-burly of life within our own cells. We'll be finding out how DNA gets damaged and repaired, and how researchers are exploiting this to find better treatments for cancer. Plus, liver from skin cells, DNA from ancient teeth, and a scary little gene of the month. Like this podcast? Please help us by supporting the Naked Scientists Every second your DNA is under assault - not just from chemicals in our environment or food, but from the hurly-burly of life within our own cells. We'll be finding out how DNA gets damaged and repaired, and how researchers are exploiting this to find better treatments for cancer. Plus, liver from skin cells, DNA from ancient teeth, and a scary little gene of the month. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:30:00 naked scientists, science, news, genes, DNA, genetics, DNA damage, DNA repair, PARP, BRCA, cancer, breast, teeth, Gremlin, butterfly, swallowtail, doublesex, liver, stem cells, reprogramming //www.silkstaq.com/guid/Naked_Genetics_14.03.14.mp3 Smells like gene spirit 24//www.silkstaq.com/podcasts/naked-genetics/smells-gene-spirit Fri, 14 Feb 2014 00:00:00 +0000 We take a look at the genetics of smell. Plus, contagious cancer, gene therapy for blindness, and a slimy gene of the month. Smell is probably the oldest sense, hardwired right into our brains and closely linked to memory. Now researchers are trying to unravel the complex genetics that underpin it. Plus, contagious dog genital cancers, gene therapy for blindness, and a rather slimy gene of the month. Like this podcast? Please help us by supporting the Naked Scientists Smell is probably the oldest sense, hardwired right into our brains and closely linked to memory. Now researchers are trying to unravel the complex genetics that underpin it. Plus, contagious dog genital cancers, gene therapy for blindness, and a rather slimy gene of the month. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:30:00 naked scientists, genes, genetics, DNA, dog, cancer, smell, scent, pheromones, coral, blindness, gene therapy, escargot, maggot //www.silkstaq.com/guid/Naked_Genetics_14.02.14.mp3 Now hear this 23//www.silkstaq.com/podcasts/naked-genetics/now-hear Tue, 14 Jan 2014 00:00:00 +0000 Hearing loss is distressing, but researchers are starting to unpick the genetic causes behind some of these problems. Hearing loss is distressing, whether it occurs later in life or in childhood. Now researchers are starting to unpick the genetic causes behind some of these problems. Plus, mice on drugs, stress and death, and a wobbly gene of the month. Like this podcast? Please help us by supporting the Naked Scientists Hearing loss is distressing, whether it occurs later in life or in childhood. Now researchers are starting to unpick the genetic causes behind some of these problems. Plus, mice on drugs, stress and death, and a wobbly gene of the month. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:30:00 naked scientists, genes, deafness, hearing, hearing loss, mice, drugs, flu, headbobber, diabetes, genetics, risk, disease, jaw, syngnathia, stress, heart, heart attack,. death //www.silkstaq.com/guid/Naked_Genetics_14.01.14.mp3 Taking shape 22//www.silkstaq.com/podcasts/naked-genetics/taking-shape Sat, 14 Dec 2013 00:00:00 +0000 Across the natural world, cells organise themselves into a wonderful array of shapes and structures. But how do they do this? Across the natural world, cells organise themselves into a wonderful array of shapes and structures. But how do they do this? Plus, building bones, plant sex in space, and a rather plump gene of the month. Like this podcast? Please help us by supporting the Naked Scientists Across the natural world, cells organise themselves into a wonderful array of shapes and structures. But how do they do this? Plus, building bones, plant sex in space, and a rather plump gene of the month. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:30:00 naked scientists, genetics, DNA, genes, shapes, bones, plants, flowers, news, snakes, hominids, Neanderthal, pollen //www.silkstaq.com/guid/Naked_Genetics_13.12.14.mp3 Come together 21//www.silkstaq.com/podcasts/naked-genetics/come-together Thu, 14 Nov 2013 00:00:00 +0000 We look at how molecules in cells self-organise to create structures, plus bee sex, tough mice, and a happily married gene of the month All living cells are made up of protein molecules - but how do they organise themselves into structures? Plus bee sex, tough mice, and a happily married gene of the month. Like this podcast? Please help us by supporting the Naked Scientists All living cells are made up of protein molecules - but how do they organise themselves into structures? Plus bee sex, tough mice, and a happily married gene of the month. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:30:00 裸体的科学家、遗传学、基因、DNA,世鹏科技电子es, cytoplasm, cytoskeleton, bee, sex, HIV, fungus, mouse, scorpion, pain, healing, matrimony, genetics, self-organisation, biophysics, models, salt, scanner //www.silkstaq.com/guid/Naked_Genetics_13.11.14.mp3 Have a heart 20//www.silkstaq.com/podcasts/naked-genetics/have-heart Mon, 14 Oct 2013 00:00:00 +0100 We take a look at the genetics of heart disease, tame the tiger genome, and our gene of the month is for hopeless romantics. The heart is a vital biological pump, beating around a billion times in a lifetime. But faulty genes can cause big problems. Plus, taming the tiger genome, solving citrus sickness, and our gene of the month is for all you hopeless romantics out there. Like this podcast? Please help us by supporting the Naked Scientists The heart is a vital biological pump, beating around a billion times in a lifetime. But faulty genes can cause big problems. Plus, taming the tiger genome, solving citrus sickness, and our gene of the month is for all you hopeless romantics out there. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:30:00 naked scientists, genes, naked genetics, heart, stroke, muamba, citrus, tiger, TCGA, cancer, stem cells, dogs, dog, dwarf, telomeres, DNA //www.silkstaq.com/guid/Naked_Genetics_13.10.14.mp3 Genes and genealogy 19//www.silkstaq.com/podcasts/naked-genetics/genes-and-genealogy Sat, 14 Sep 2013 00:00:00 +0100 Who do you think you are? And is the answer in your genes? This month we're delving into genes and genealogy. Who do you think you are? And is the answer in your genes? This month we're delving into genes and genealogy. Plus, putting an end to genetic determinism, and an ancient Egyptian gene of the month. Like this podcast? Please help us by supporting the Naked Scientists Who do you think you are? And is the answer in your genes? This month we're delving into genes and genealogy. Plus, putting an end to genetic determinism, and an ancient Egyptian gene of the month. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:30:00 naked scientists, genetics, genes, genealogy, Vikings, DNA, stem cells, cancer, Huntington's disease, stress, Cleopatra //www.silkstaq.com/guid/Naked_Genetics_13.09.14.mp3 Genes, infections and immunity 18//www.silkstaq.com/podcasts/naked-genetics/genes-infections-and-immunity Wed, 14 Aug 2013 00:00:00 +0100 Why can some people stay fit as a fiddle, while other seem to catch every bug that's going? The answer lies in our genes. Why can some people stay fit as a fiddle, while other seem to catch every bug that's going? As you might expect, the answer lies in our genes. Plus, a multitude of mutant mice, the state of gene therapy for epilepsy, and an unseeing gene of the month. Like this podcast? Please help us by supporting the Naked Scientists Why can some people stay fit as a fiddle, while other seem to catch every bug that's going? As you might expect, the answer lies in our genes. Plus, a multitude of mutant mice, the state of gene therapy for epilepsy, and an unseeing gene of the month. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:30:00 naked scientists, podcast, genetics, news, immune system, immunity, bacteria, infection, sepsis, lung cancer, cancer, mouse, mutant, mutation, sickness, evolution, obesity, fat, cholera, stem cells, reprogramming, childhood, children, eyes, epilepsy //www.silkstaq.com/guid/Naked_Genetics_13.08.14.mp3 Let's talk about sex 17//www.silkstaq.com/podcasts/naked-genetics/lets-talk-about-sex Sun, 14 Jul 2013 00:00:00 +0100 Summer loving is in the air, so what better time to think about sex? We're talking about the genetics of sex determination Summer loving is in the air, so what better time to think about sex? But we're not going to get graphic - we're talking about the genetics of sex determination. Plus, why turkeys need a wingman, figuring out fingerprints, and a leggy gene of the month. Like this podcast? Please help us by supporting the Naked Scientists Summer loving is in the air, so what better time to think about sex? But we're not going to get graphic - we're talking about the genetics of sex determination. Plus, why turkeys need a wingman, figuring out fingerprints, and a leggy gene of the month. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:30:00 naked scientists, news, genetics, sex, science, chromosomes, birds, SIRT1, mice, humans, genes, DNA, female, male, Myrida, BRCA, cancer, hybrid, embryos, antennapedia, Hox, fingerprints, fertility, circadian, body clock, ageing //www.silkstaq.com/guid/Naked_Genetics_13.07.14.mp3 The future of fingerprinting 16//www.silkstaq.com/podcasts/naked-genetics/future-fingerprinting Fri, 14 Jun 2013 00:00:00 +0100 Our genes are our unique calling card and DNA analysis can solve crimes and resolve family disputes. And it's set to revolutionise medicine. Our genes are our unique calling card, and DNA analysis has been used to solve crimes and resolve paternity disputes for decades. Now new genetic technology promises to revolutionise medicine. Plus, we meet the man who invented genetic fingerprinting, discuss Angelina Jolie's breasts, and savour a cheesy gene of the month. Like this podcast? Please help us by supporting the Naked Scientists Our genes are our unique calling card, and DNA analysis has been used to solve crimes and resolve paternity disputes for decades. Now new genetic technology promises to revolutionise medicine. Plus, we meet the man who invented genetic fingerprinting, discuss Angelina Jolie's breasts, and savour a cheesy gene of the month. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:30:00 naked scientists, genes, DNA, fingerprinting, crime, paternity, family history, genealogy, tricorder, star trek, Spock, medicine, cancer, mosquitoes, Angelina jolie, breast, heart, motor neurone, ALS, skin colour, pigment //www.silkstaq.com/guid/Naked_Genetics_13.06.14.mp3 Genomics - Hope or hype? 15//www.silkstaq.com/podcasts/naked-genetics/genomics-hope-or-hype Tue, 14 May 2013 00:00:00 +0100 基因技术是扩张速度can keep up with, but is this explosion of information delivering advances for patients? 基因技术是扩张速度can keep up with, with huge amounts of data being generated every week. But is this explosion of information delivering meaningful advances for patients? Plus, how one scientist tracked down the gene fault behind his own disease, what sequencing the HeLa genome means for genetic privacy, and a Pythonesque gene of the month. Like this podcast? Please help us by supporting the Naked Scientists 基因技术是扩张速度can keep up with, with huge amounts of data being generated every week. But is this explosion of information delivering meaningful advances for patients? Plus, how one scientist tracked down the gene fault behind his own disease, what sequencing the HeLa genome means for genetic privacy, and a Pythonesque gene of the month. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:30:00 naked scientists, genetics, genes, DNA, disease, duchenne, muscular dystrophy, genomics, sequencing, news, science, HeLa, turtle, rare diseases, //www.silkstaq.com/guid/Naked_Genetics_13.05.14.mp3 Doing the twist - packing DNA 14//www.silkstaq.com/podcasts/naked-genetics/doing-twist-packing-dna Sun, 14 Apr 2013 00:00:00 +0100 Almost every single cell of your body is packed with more than two metres of DNA, but how does it all get in there? Almost every single cell of your body is packed with more than two metres of DNA, containing your genes. But not only does it have to be packed up to fit in there, it also has to be organised and read. Plus, how genetic variations are linked to cancer risk,analysing dinosaur DNA, and an adventurous gene of the month. Like this podcast? Please help us by supporting the Naked Scientists Almost every single cell of your body is packed with more than two metres of DNA, containing your genes. But not only does it have to be packed up to fit in there, it also has to be organised and read. Plus, how genetic variations are linked to cancer risk,analysing dinosaur DNA, and an adventurous gene of the month. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:30:00 naked scientists, genes, genetics, society, genomics, chromosomes, histones, chromatin, topoisomerase, twist, DNA, Antarctic, frui fly, dinosaur, //www.silkstaq.com/guid/Naked_Genetics_13.04.14.mp3 Beautiful otherness - autism genetics 13//www.silkstaq.com/podcasts/naked-genetics/beautiful-otherness-autism-genetics Thu, 14 Mar 2013 00:00:00 +0000 It's thought that around one in a hundred children in the UK is somewhere on the autistic spectrum - a complex range of disorders. It's thought that around one in a hundred children in the UK is somewhere on the autistic spectrum - a complex range of disorders that can be challenging to understand and live with. But recent advances in genetics are bringing hope for new therapies that might help. Plus, we look at the genes underlying Specific Language Impairment, find out why cancer has the X factor, and meet a hopeless-sounding gene of the month. Like this podcast? Please help us by supporting the Naked Scientists It's thought that around one in a hundred children in the UK is somewhere on the autistic spectrum - a complex range of disorders that can be challenging to understand and live with. But recent advances in genetics are bringing hope for new therapies that might help. Plus, we look at the genes underlying Specific Language Impairment, find out why cancer has the X factor, and meet a hopeless-sounding gene of the month. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:30:00 genes, autism, language, SLI, lamprey, vitiligo, protein, sequence, transcription, RNA, DNA, genetics, cancer, nerves, brain, //www.silkstaq.com/guid/Naked_Genetics_13.03.14.mp3 The wonderful world of RNA 12//www.silkstaq.com/podcasts/naked-genetics/wonderful-world-rna Thu, 14 Feb 2013 00:00:00 +0000 You've probably heard of DNA, but what do you know about RNA? As well as being the molecule that shuttles information from our genes into our cells, it also plays a huge number of other roles in all cells, from bacteria and viruses to tiny... You've probably heard of DNA, but what do you know about RNA? As well as being the molecule that shuttles information from our genes into our cells, it also plays a huge number of other roles in all cells, from bacteria and viruses to tiny worms, plants and humans. Plus we delve into quadruplex DNA, wonder about the wolf genome, speculate on skin colour and our gene of the month has a literary twist. Like this podcast? Please help us by supporting the Naked Scientists You've probably heard of DNA, but what do you know about RNA? As well as being the molecule that shuttles information from our genes into our cells, it also plays a huge number of other roles in all cells, from bacteria and viruses to tiny worms, plants and humans. Plus we delve into quadruplex DNA, wonder about the wolf genome, speculate on skin colour and our gene of the month has a literary twist. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:30:00 science, genetics, genes, worms, plants, bacteria, viruses, flies, sherry dogs, quadruplex, DNA, RNA, cancer, disease, telomeres, telomerase, heart, //www.silkstaq.com/guid/Naked_Genetics_13.02.14.mp3 Fitting into your genes - the genetics of obesity 11//www.silkstaq.com/podcasts/naked-genetics/fitting-your-genes-genetics-obesity Mon, 14 Jan 2013 00:00:00 +0000 The gym is full, the pubs are empty - it can only be January, as a good proportion of the population resolves to shape up and lose weight. The gym is full, the pubs are empty - it can only be January, as a good proportion of the population resolves to shape up and lose weight. But are your efforts going to help you fit into your jeans (with a J), or are you just fighting against your genes (with a G)? Plus, we discuss how genes might jump between cows and snakes, and we've got gout, goats, giant pandas and a glass bottom boat.This is the Naked Genetics podcast for January 2013 with me, Dr Kat Arney, brought to you in association with The Genetics Society, online at genetics.org.uk. Like this podcast? Please help us by supporting the Naked Scientists The gym is full, the pubs are empty - it can only be January, as a good proportion of the population resolves to shape up and lose weight. But are your efforts going to help you fit into your jeans (with a J), or are you just fighting against your genes (with a G)? Plus, we discuss how genes might jump between cows and snakes, and we've got gout, goats, giant pandas and a glass bottom boat.This is the Naked Genetics podcast for January 2013 with me, Dr Kat Arney, brought to you in association with The Genetics Society, online at genetics.org.uk. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:30:00 fat, obesity, diabetes, metabolism, gout, goat, flies, cancer, genes, genetics, panda, snake, cow //www.silkstaq.com/guid/Naked_Genetics_13.01.14.mp3 Cancer genetics - When good cells go bad 10//www.silkstaq.com/podcasts/naked-genetics/cancer-genetics-when-good-cells-go-bad Fri, 14 Dec 2012 00:00:00 +0000 Cancer is literally the enemy within us, starting when good cells go rogue. But how can we use new genetic knowledge to beat it? Cancer is literally the enemy within us -it starts when our own cells get damaged and go rogue, multiplying out of control and spreading around body. But how can we use new genetic knowledge to beat it? Plus, decoding the wheat genome, finding out where birds came from, and our gene of the month is more art than science. Like this podcast? Please help us by supporting the Naked Scientists Cancer is literally the enemy within us -it starts when our own cells get damaged and go rogue, multiplying out of control and spreading around body. But how can we use new genetic knowledge to beat it? Plus, decoding the wheat genome, finding out where birds came from, and our gene of the month is more art than science. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:30:00 cancer, DNA, genetics, genome, birds, evolution, Huntingtons, disease, genomics, wheat, pancreatic, brain, dinosaur //www.silkstaq.com/guid/Naked_Genetics_12.12.14.mp3 The genetics of germs 9//www.silkstaq.com/podcasts/naked-genetics/genetics-germs Wed, 14 Nov 2012 00:00:00 +0000 Our world - and our bodies - are teeming with bacteria. And although some of them are friendly, many of them are not. Our world - and our bodies - are teeming with bacteria. And although some of them are friendly, many of them are not. Plus, electrifying news about bacterial nanowires, cuddly koalas, and counting chromosomes, and our gene of the month is the mindblowing Mind Bomb. Like this podcast? Please help us by supporting the Naked Scientists Our world - and our bodies - are teeming with bacteria. And although some of them are friendly, many of them are not. Plus, electrifying news about bacterial nanowires, cuddly koalas, and counting chromosomes, and our gene of the month is the mindblowing Mind Bomb. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:30:00 koalas,irritable bowel syndrome,bioengineer,nanowire, chromosome,bowel,hearing,bacteria, germs, cystitis, UTI,scientists,naked scientists, placebo, outbreak, genome, sequencing, diversity, mindbomb //www.silkstaq.com/guid/Naked_Genetics_12.11.14.mp3 Stop bugging me! The genetics of bedbugs and other insects 8//www.silkstaq.com/podcasts/naked-genetics/stop-bugging-me-genetics-bedbugs-and-other-insects Sun, 14 Oct 2012 00:00:00 +0100 They suck your blood, hitch-hike on your luggage, and are a growing threat to the hotel industry. Bedbugs are a growing problem in the modern jet-set world, and scientists are using genetic techniques to try and understand why. Feeling... They suck your blood, hitch-hike on your luggage, and are a growing threat to the hotel industry. Bedbugs are a growing problem in the modern jet-set world, and scientists are using genetic techniques to try and understand why. Feeling itchy yet? Plus, we look at the genetics of some other annoying insects, get to the bottom of the recent controversy about junk DNA, and our gene of the month is none other than Superman and his weedier alter-ego Clark Kent. Like this podcast? Please help us by supporting the Naked Scientists They suck your blood, hitch-hike on your luggage, and are a growing threat to the hotel industry. Bedbugs are a growing problem in the modern jet-set world, and scientists are using genetic techniques to try and understand why. Feeling itchy yet? Plus, we look at the genetics of some other annoying insects, get to the bottom of the recent controversy about junk DNA, and our gene of the month is none other than Superman and his weedier alter-ego Clark Kent. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:30:00 naked scientists, genetics, genes, bedgbugs, DNA, stem cells, mosquitoes, fruit flies, disease, parasites, ENCODE, junk DNA, genome, oyster, plants, genetic engineering, cheetah, spots, stripes, deafness, gerbil //www.silkstaq.com/guid/Naked_Genetics_12.10.14.mp3 Epigenetics and reprogramming - turning back the clock 7//www.silkstaq.com/podcasts/naked-genetics/epigenetics-and-reprogramming-turning-back-clock Fri, 14 Sep 2012 00:00:00 +0100 我们都听过的遗传密码——字母that spell out the instructions in our DNA. But that's not the whole story. Researchers are increasingly digging into the epigenetic code - the marks that tell cells which genes to use and... 我们都听过的遗传密码——字母that spell out the instructions in our DNA. But that's not the whole story. Researchers are increasingly digging into the epigenetic code - the marks that tell cells which genes to use and which to ignore. Plus, we take a look behind the headlines about older fathers and autism, find out what chimps can tell us about our cancer risk, and our gene of the month might be mistaken for a heavy metal band. Like this podcast? Please help us by supporting the Naked Scientists 我们都听过的遗传密码——字母that spell out the instructions in our DNA. But that's not the whole story. Researchers are increasingly digging into the epigenetic code - the marks that tell cells which genes to use and which to ignore. Plus, we take a look behind the headlines about older fathers and autism, find out what chimps can tell us about our cancer risk, and our gene of the month might be mistaken for a heavy metal band. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:30:00 cancer, DNA, reprogramming, autism, epigenetic, naked scientists, genome, fathers, news, science, genetics, stem cells //www.silkstaq.com/guid/Naked_Genetics_12.09.14.mp3 Genes and genomes 6//www.silkstaq.com/podcasts/naked-genetics/genes-and-genomes Tue, 14 Aug 2012 00:00:00 +0100 现在是十多年以来,人类基因组first sequenced, costing over a billion pounds and taking 13 years. Today, we're close to the thousand dollar genome. But what's in a genome, and what can it tell us about our risk of... 现在是十多年以来,人类基因组first sequenced, costing over a billion pounds and taking 13 years. Today, we're close to the thousand dollar genome. But what's in a genome, and what can it tell us about our risk of disease? Plus we'll be arguing the age of polar bears, and finding out about fish with skin cancer. And our gene of the month is one for the Trekkies out there - it's Tribbles. Like this podcast? Please help us by supporting the Naked Scientists 现在是十多年以来,人类基因组first sequenced, costing over a billion pounds and taking 13 years. Today, we're close to the thousand dollar genome. But what's in a genome, and what can it tell us about our risk of disease? Plus we'll be arguing the age of polar bears, and finding out about fish with skin cancer. And our gene of the month is one for the Trekkies out there - it's Tribbles. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:30:00 naked scientists, genetics, genes, genomes, junk DNA, Sanger, sequence, polar bear, fish, melanoma, evolution, teeth, tooth, stem cell, risk, disease, eggs, twins, siblings, Tribbles, epilepsy, blindness, hemiplegia, heart //www.silkstaq.com/guid/Naked_Genetics_12.08.14.mp3 Hacking biology - synthetic DNA and experimental evolution 5//www.silkstaq.com/podcasts/naked-genetics/hacking-biology-synthetic-dna-and-experimental-evolution Sat, 14 Jul 2012 00:00:00 +0100 Every biology student is familiar with DNA - the ladder-like blueprint of life built on a backbone of the sugar deoxyribose. Scientists are now hacking this structure to make entirely new DNA-like molecules built on different sugar... Every biology student is familiar with DNA - the ladder-like blueprint of life built on a backbone of the sugar deoxyribose. Scientists are now hacking this structure to make entirely new DNA-like molecules built on different sugar skeletons, opening an exciting new world of synthetic genetics. Plus, we find out what happens when music has sex, discover why the X chromosome is more than just a number, and our gene of the month is the unfortunate Ken and Barbie. Like this podcast? Please help us by supporting the Naked Scientists Every biology student is familiar with DNA - the ladder-like blueprint of life built on a backbone of the sugar deoxyribose. Scientists are now hacking this structure to make entirely new DNA-like molecules built on different sugar skeletons, opening an exciting new world of synthetic genetics. Plus, we find out what happens when music has sex, discover why the X chromosome is more than just a number, and our gene of the month is the unfortunate Ken and Barbie. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:30:06 translocation,ripening,dna sequencing,MRC,damp,skeleton,rna,transparent,storage,spine,backbone,sex,driving,ring,attention,online,driv,male,face,fly,proteins,LED,particl,pattern,particle,fish,development,pow,naked scientist,journal,molecule,fast,cell,scien //www.silkstaq.com/guid/Naked_Genetics_12.07.14.mp3 Tackling neurodegenerative diseases 4//www.silkstaq.com/podcasts/naked-genetics/tackling-neurodegenerative-diseases Thu, 14 Jun 2012 00:00:00 +0100 Complex, mysterious and currently incurable - the challenge for researchers working on neurodegenerative diseases is huge. We'll be finding out how scientists are using genetic approaches to understand these distressing illnesses. Complex, mysterious and currently incurable - the challenge for researchers working on neurodegenerative diseases is huge. We'll be finding out how scientists are using genetic approaches to understand these distressing illnesses. Plus we find out why claims of a male contraceptive pill are somewhat premature, discover how a 16th century mummy has revealed the history of hepatitis B, and investigate whether your genes could predispose you to life in orbit. And our gene of the month is the hollow-sounding Tinman. Like this podcast? Please help us by supporting the Naked Scientists Complex, mysterious and currently incurable - the challenge for researchers working on neurodegenerative diseases is huge. We'll be finding out how scientists are using genetic approaches to understand these distressing illnesses. Plus we find out why claims of a male contraceptive pill are somewhat premature, discover how a 16th century mummy has revealed the history of hepatitis B, and investigate whether your genes could predispose you to life in orbit. And our gene of the month is the hollow-sounding Tinman. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:30:13 赤裸裸的科学家、大脑、神经退化,生物学cs, medicine, MND, motor neurone, ALS, stem cells, mouse, Lou Gehrig's //www.silkstaq.com/guid/Naked_Genetics_12.06.14.mp3 The world of top (genetics) models 3//www.silkstaq.com/podcasts/naked-genetics/world-top-genetics-models Mon, 14 May 2012 00:00:00 +0100 This month we're taking a look at the world of top models - not the kind that won't get out of bed for less than ten grand, but the model organisms used by researchers all over the world to answer some of the most challenging questions in... This month we're taking a look at the world of top models - not the kind that won't get out of bed for less than ten grand, but the model organisms used by researchers all over the world to answer some of the most challenging questions in biology. We'll also be hearing about the origins of polar bears, the extinction of Tasmanian tigers, fitter frogs with faster-changing genomes and promiscuous bees. And move over Beyonce, because our gene of the month is the curvaceous Callipyge - Greek for beautiful buttocks. Like this podcast? Please help us by supporting the Naked Scientists This month we're taking a look at the world of top models - not the kind that won't get out of bed for less than ten grand, but the model organisms used by researchers all over the world to answer some of the most challenging questions in biology. We'll also be hearing about the origins of polar bears, the extinction of Tasmanian tigers, fitter frogs with faster-changing genomes and promiscuous bees. And move over Beyonce, because our gene of the month is the curvaceous Callipyge - Greek for beautiful buttocks. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:28:57 naked scientists, genetics, plants, worms, models, news, questions, DNA, //www.silkstaq.com/guid/May2012_final.mp3 Developmental genetics - from one cell to many 2//www.silkstaq.com/podcasts/naked-genetics/developmental-genetics-one-cell-many 坐,2012年4月14日00:00:00 +0100 This month we're taking a trip into the world of developmental genetics, finding out how an animal grows from one cell into many millions as it develops from a fertilised egg, and discovering how it knows when it's grown enough. We also... This month we're taking a trip into the world of developmental genetics, finding out how an animal grows from one cell into many millions as it develops from a fertilised egg, and discovering how it knows when it's grown enough. We also hear about the hunt for genes involved in autism, see what sticklebacks can tell us about evolution, ponder the purpose of keeping 9,000 placentas, and ask whether we can ever genetically engineer humans to drink seawater. And the monster raving loony gene of the month is the wacky-sounding Lunatic Fringe. Like this podcast? Please help us by supporting the Naked Scientists This month we're taking a trip into the world of developmental genetics, finding out how an animal grows from one cell into many millions as it develops from a fertilised egg, and discovering how it knows when it's grown enough. We also hear about the hunt for genes involved in autism, see what sticklebacks can tell us about evolution, ponder the purpose of keeping 9,000 placentas, and ask whether we can ever genetically engineer humans to drink seawater. And the monster raving loony gene of the month is the wacky-sounding Lunatic Fringe. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:32:18 naked scientists, questions, genetics, genes, development, size, drosophila, //www.silkstaq.com/guid/Naked_Genetics_12.04.05.mp3 Genes and evolution - from populations to tumours 1//www.silkstaq.com/podcasts/naked-genetics/genes-and-evolution-populations-tumours Wed, 14 Mar 2012 00:00:00 +0000 From whole populations to individual cancers, we're taking a look at genes and evolution. We're also talking about dogs and their diseases, shining a light on Van Gogh's sunflowers, and wondering whether the USB-sized DNA sequence is hope... From whole populations to individual cancers, we're taking a look at genes and evolution. We're also talking about dogs and their diseases, shining a light on Van Gogh's sunflowers, and wondering whether the USB-sized DNA sequence is hope or hype. Plus we've got our gene of the month - whether it's Sonic, Desert or Indian, we'll be carefully getting to grips with the prickly persona of the hedgehog gene. Like this podcast? Please help us by supporting the Naked Scientists From whole populations to individual cancers, we're taking a look at genes and evolution. We're also talking about dogs and their diseases, shining a light on Van Gogh's sunflowers, and wondering whether the USB-sized DNA sequence is hope or hype. Plus we've got our gene of the month - whether it's Sonic, Desert or Indian, we'll be carefully getting to grips with the prickly persona of the hedgehog gene. Like this podcast? Please help us by supporting the Naked Scientists 菲尔·桑塞姆 no full 00:32:40 naked scientists, evolution, cancer, genes, genetics, humans, Darwin, natural selection, science //www.silkstaq.com/guid/Naked_Genetics_12.03.05.mp3