过多的钙会使你的骨头变脆吗?

令人惊讶的是，答案是肯定的。钙与磷酸盐结合，形成化学物质“磷灰石”(磷酸钙)，这是我们所知道的最坚硬的化学物质之一，正是它使骨骼坚硬、坚硬。但如果你摄入过多的钙，那就和摄入太少一样糟糕，就像骨质疏松症一样，骨骼实际上开始失去钙化和骨骼基质，这使它们变得脆弱，更容易断裂。还有另一种疾病叫做“骨软化症”，你体内的钙太少，也会使骨骼变弱。但有些人实际上在骨骼中储存了过多的钙，这种情况被称为“骨质疏松症”，来自“石质”。这是人们骨骼中钙含量的五倍。这是一种遗传疾病。这是非常罕见的，我认为它也被称为阿尔伯斯-勋伯格病或类似的东西，但它非常罕见。在这些个体中，分解骨骼的细胞，称为“破骨细胞”，不能正常工作。这是因为骨骼的正常形成方式涉及到新骨的生成和旧骨的分解之间的平衡，这就是骨骼不断重塑的方式。 So if you shift that equilibrium on one direction or the other, you either lose or gain bone. And what scientists have found is that in people who have osteopetrosis, the osteoclasts that normally breakdown bone cannot work properly. They have a deficiency of an enzyme called "carbonic anhydrase" and you need that to break down the calcium phosphate, the apatite, in order to remodel the bone. As a result, they just keep on making their bones get harder and harder, and harder. Eventually they go beyond the point of this being beneficial and the bones become less flexible and more likely to break, so they get very brittle.